ArticleMaterials today. Bio2025
FGF mimetic peptide-modified electrospun nanocomposite fibrous membranes for accelerating infectious diabetic wound healing by synergistic antibacterial and pro-angiogenesis effects.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Sprayable NIR/pH-responsive NSC/PF127 hydrogel loaded with MoO₂, ciprofloxacin, and FGF-2 for enhanced antibacterial and pro-regenerative infected wound healing.Drug delivery · 2026Article
- Alkaloid-based nanodrug delivery systems: An emerging strategy against drug-resistant bacterial wound infections.International journal of pharmaceutics: X · 2026Review
- Self-assembling nanocomposites for smart drug delivery: towards personalized and stimuli-responsive therapeutics.RSC advances · 2026Review
- Therapeutic effect of sustained release of aloe emodin via novel grafted polymer in electrospun nanofiber membranes on peritendinous adhesions.Frontiers in bioengineering and biotechnology · 2026Article
- Heterogeneous zinc/catechol-derived resin microsphere-functionalized composite hydrogels with antibacterial and anti-inflammatory activities promote bacterial-infected wound healing.Regenerative biomaterials · 2025Article
- Mechanisms, strategies, and clinical application progress of subcutaneous transplantation angiogenesis.Frontiers in bioengineering and biotechnology · 2025Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic wound treatment remains a severe threat to public health. Biomimetic nanocomposite scaffolds have shown great potential in anti-infection, but the challenges associated with insufficient angiogenesis remain. Herein, an efficient nanocomposite membrane combining basic fibroblast growth factor (FGF2) mimetic peptides and copper/catechol-derived resin nanoparticles (CuCFR NPs) loaded poly(L-lactide-co-ε-caprolactone) (PLCL) electrospun fibrous membrane was developed for accelerating infectious diabetic wound healing by synergistic antibacterial and pro-angiogenesis effects. FGF2 mimetic peptides were chemically grafted onto the surface of the membrane to impart efficient cell viability while maintaining the porous ultrafine-fiber morphology, large tensile strength of 6.2 MPa and elongation of 317 %. The liberation of FGF2 mimetic peptides from the membrane effectively promoted both fibroblast and endothelial cell proliferation, migration, and enhanced tube formation
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Registered trials
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