ArticleFrontiers in oncology2025
Different risk factors for multiple and unifocal gliomas: a comparative study of radiological, pathological and clinical characteristics.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This retrospective study compared two types of gliomas and two subtypes of multiple gliomas. Methods: The clinical manifestations, magnetic resonance imaging (MRI) findings, pathological characteristics, and clinical outcomes of 188 patients with unifocal and 94 patients with multiple gliomas (59 with multifocal and 35 with multicentric gliomas) were analyzed. Results: Compared with patients with unifocal glioma, those with multiple gliomas were older ( Conclusions: The demographic characteristics, extent of resection, radiological features, pathological features and prognostic factors differ between patients with multiple gliomas and those with unifocal gliomas. The clinical and radiological features differ between patients with different subtypes of multiple gliomas. Multiple gliomas located only in superficial regions are more likely to be multicentric gliomas and the prognosis is solely related to the WHO grades, providing valuable guidance for clinical treatment.
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