Evidence map›Paper›PMID 40496605›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Severe Unilateral Alopecia in a Long-Term Surviving Male Adolescent Glioblastoma Multiforme Patient.

Ling Xiong, Lan Mao, Yuesi Qin, Xia Xiong, Yongqiong Deng

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling Xiong *Department of Dermatology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China.ORCID 0009-0004-5545-2757
Lan Mao *Department of Dermatology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China.ORCID 0009-0004-6841-0054
Yuesi QinDepartment of Dermatology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, People's Republic of China.
Xia XiongDepartment of Dermatology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China.ORCID 0000-0002-2564-7850
Yongqiong DengDepartment of Dermatology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radiation-induced alopecia (RIA) typically presents as transiently or persistently non-scarring alopecia with a distinct geometric pattern, and minoxidil sometimes serves as an effective therapeutic agent. However, there have been no reported cases of severe unilateral alopecia following radiotherapy for pediatric glioblastoma multiforme (p-GBM), that was unresponsive to minoxidil treatment. Case Report: This case presents a 17-year-old male with severe unilateral alopecia, who was diagnosed with glioblastoma multiforme (GBM) and consequently received radiochemotherapy. Remarkably, he has survived beyond three years without evidence of tumor recurrence, but with the sole persistent issue being the left-sided alopecia. Despite intensive therapeutic interventions comprising 12 months of topical 5% minoxidil therapy (twice daily) combined with three courses of platelet-rich plasma (PRP) injections administered at 4-week intervals, the alopecic area showed no significant improvement and eventually progressed to permanent alopecia. Conclusion: The prevention and treatment of RIA remain poorly understood, and this clinical scenario urgently necessitates the exploration of novel therapeutic strategies.

Indexed as

alopeciachemoradiotherapy alopeciaglioblastoma multiforme (GBM)pediatric glioblastoma multiforme (p-GBM)severe unilateral alopecia

Identifiers

PMID40496605
PMCPMC12151158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.