Evidence map›Paper›PMID 40496597›Full record

ArticleOrthopaedic journal of sports medicine2025

Septic Arthritis After Anterior Cruciate Ligament Reconstruction: A Comparative Study of Pediatric, Adolescent, and Young Adult Populations.

Deepak Chona, Jeffrey Kay, Nazgol Tavabi, Michael Quinn, Dennis Kramer, Yi-Meng Yen, Melissa Ann Christino, Matthew Milewski, Mininder S Kocher, James Pruneski and 2 more

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Deepak ChonaBoston Children's Hospital, Boston, Massachusetts, USA.
Jeffrey KayBoston Children's Hospital, Boston, Massachusetts, USA.
Nazgol TavabiBoston Children's Hospital, Boston, Massachusetts, USA.
Michael QuinnBoston Children's Hospital, Boston, Massachusetts, USA.
Dennis KramerBoston Children's Hospital, Boston, Massachusetts, USA.
Yi-Meng YenBoston Children's Hospital, Boston, Massachusetts, USA.
Melissa Ann ChristinoBoston Children's Hospital, Boston, Massachusetts, USA.
Matthew MilewskiBoston Children's Hospital, Boston, Massachusetts, USA.
Mininder S KocherBoston Children's Hospital, Boston, Massachusetts, USA.
James PruneskiBoston Children's Hospital, Boston, Massachusetts, USA.
Ata KiapourBoston Children's Hospital, Boston, Massachusetts, USA.
Benton E HeyworthBoston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2572-1344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited evidence exists regarding septic arthritis (SA) after anterior cruciate ligament reconstruction (ACLR) in pediatric and adolescent patients. Purpose/Hypothesis: The purpose of this study was to compare post-ACLR SA cases during a 21-year period in pediatric and adolescent patients to those in a young adult control cohort. It was hypothesized that the incidence would be similarly low in both subpopulations. Study Design: Case series; Level of evidence, 4. Methods: Records of patients who underwent ACLR between 2000 and 2020 were retrospectively reviewed for diagnoses of postoperative SA of the ipsilateral knee, defined by culture-positive arthrocentesis or synovial fluid white blood cell count >50,000 cells/mL. Surgical details, culture results, and clinical course were analyzed. Age-based cohorts-pediatric (<13 years of age), adolescent (13-19 years of age), and young adult (20-35 years of age)-were compared using chi-square tests for age, graft source, graft type, concurrent meniscal procedures, and SA incidence. Time between ACLR and subsequent surgeries was analyzed utilizing Results: Of 5638 ACLR cases (pediatric: n = 606, 10.7%; adolescent: n = 4123, 73.1%; young adult: n = 909, 16.1%), SA was diagnosed in 13 patients (0.23%; adolescent: n = 12, 0.30%; young adult: n = 1, 0.11%) a median of 15 days (range 6-632 days) after ACLR. One or more arthroscopic irrigation and debridement (I&Ds) (mean, 2; range, 1-3) were performed, and anterior cruciate ligament (ACL) grafts were retained for all patients. The mean clinical follow-up was 3.5 years (range, 0.6-9.2 years). Subsequent surgeries include 2 lysis of adhesions, 3 meniscectomies, 1 meniscal repair, 3 patellar chondroplasties, 1 loose-body removal, 2 patellar biopsies, 1 debridement, and 1 revision ACLR 6 years postoperatively for acute ACL graft rupture. The most common microbes were Conclusion: Post-ACLR SA was similarly rare for adolescents and young adults, and no cases were identified in 606 pediatric patients. No associations were identified between SA and demographic factors, graft source, graft type, or concurrent meniscal surgery.

Indexed as

ACLadolescentpediatricseptic arthritis

Identifiers

PMID40496597
PMCPMC12149631

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