Evidence map›Paper›PMID 40496580›Full record

ArticleHeart rhythm O22025

Agreement on site of latest electrical activation between right ventricular pacing and intrinsic conduction as target for left ventricular lead position in cardiac resynchronization therapy.

Henrik Laurits Bjerre, Jens Cosedis Nielsen, Anders Lehmann Dahl Pedersen, Christian Gerdes, Jens Kristensen, Jesper Møller Jensen, Bjarne Linde Nørgaard, Mads Brix Kronborg

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Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Henrik Laurits BjerreDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Jens Cosedis NielsenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Anders Lehmann Dahl PedersenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Christian GerdesDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Jens KristensenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Jesper Møller JensenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Bjarne Linde NørgaardDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Mads Brix KronborgDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In cardiac resynchronization therapy (CRT), studies indicate that targeting the left ventricular (LV) lead toward the site of latest electrical activation could improve clinical outcomes. Whether this site should be determined during right ventricular (RV) pacing or intrinsic conduction is unknown. Objective: The study sought to investigate agreement between RV pacing and intrinsic conduction in identifying the site of latest electrical activation in patients undergoing CRT. Methods: During CRT implantation, we obtained pairwise measurements of the interval from QRS onset to local LV activation during intrinsic conduction (Q-LV) and the interval from the paced signal on the RV lead electrogram to the sensed local LV activation during RV pacing (RV Results: We included 61 patients and measured intervals in 209 veins with 531segments. We found substantial agreement between RV Conclusion: There is substantial agreement between RV

Indexed as

Agreement analysisCardiac deviceCardiac resynchronization therapyCRTHeart failureRV pacingTargeted positioning

Identifiers

PMID40496580
PMCPMC12147583

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.