ReviewHeart rhythm O22025
Ischemia induced repolarization dispersion changes and ventricular arrhythmia: Validation of Frank vectorcardiography parameters: A review.
Review in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Repolarization adaptation to rapid change in heart rate in human models - a review.The Journal of physiology · 2026Review
- Source-Only Transportability of Engineered ECG Features for Healthy-Versus-Myocardial Infarction Classification.Diagnostics (Basel, Switzerland) · 2026Article
- LQT1 patients have augmented response of repolarization dispersion following atropine induced heart rate increase versus healthy controls.Physiological reports · 2026Article
- ECG-Guided Antiarrhythmic Therapy in Acute Coronary Syndrome: A Multidimensional Assessment of Biomarkers, Cardiac Function, and Quality of Life.Therapeutics and clinical risk management · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in dispersion of ventricular repolarization is a salient electrophysiological feature of acute myocardial ischemia and linked to life-threatening arrhythmias. In 9 studies, we applied Frank vectorcardiography not only for noninvasive monitoring of cardiac electrophysiology during acute ischemia induced during percutaneous coronary interventions, during clinical myocardial infarction, and in an occlusion-reperfusion pig model, but also for prognostic purposes after coronary events. Myocardial ischemia was in humans and pigs associated with significant changes in the ST segment, Tamplitude, Tarea, ventricular gradient, and T vector loop morphology. In the pig model, a link between dispersion changes and the occurrence and suppression (by spinal cord stimulation) of ventricular arrhythmias was found. Prognostically, after recent acute coronary events, the spatial peak and mean QRS-T angles were superior. In summary, vectorcardiography-based parameters were validated as reflecting changes in repolarization dispersion during myocardial ischemia in humans and pigs, and in pigs linked to the occurrence and suppression of ventricular arrhythmias.
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Registered trials
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