Evidence map›Paper›PMID 40496557›Full record

ArticleFrontiers in endocrinology2025

Hashimoto's thyroiditis and its activity status influence the assessment of lymph node metastasis of thyroid cancer.

Caigu Yan, Yuxuan Zhao, Qingyu Zhang, Xianghui He

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caigu Yan *Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yuxuan Zhao *Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, China.
Qingyu ZhangDepartment of Gastroenterology, Tianjin Medical University General Hospital, Tianjin, China.
Xianghui HeDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Hashimoto's thyroiditis plays a crucial role in the biological behavior of papillary thyroid carcinoma. The purpose of this study was to explore the impact of Hashimoto's thyroiditis on the preoperative evaluation of thyroid cancer. Method: Univariate and multivariate analyses were performed to explore the clinicopathological characteristics and the risk factors for lymph node metastasis (LNM) in 2,261 patients with papillary thyroid carcinoma. Results: The clinical data showed that the clinicopathological characteristics varied in different states of Hashimoto's thyroiditis and levels of the thyroid peroxidase (TPO) antibody ( Conclusion: Hashimoto's thyroiditis can affect the preoperative evaluation of thyroid cancer. In addition, sex might affect the biological behavior of papillary thyroid carcinoma, which may result from the different immune and cellular statuses among different sexes and ages.

Indexed as

Hashimoto DiseaseLymphatic MetastasisThyroid Cancer, PapillaryThyroid NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsHashimoto’simmune infiltrationlymph nodes metastasispapillary thyroid carcinomasonography

Identifiers

PMID40496557
PMCPMC12148851

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.