ArticleWorld journal of cardiology2025
Multimodal analgesia in cardiac surgery: Impact on postoperative medication consumption and cognitive function.
Article in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Goal-directed multimodal analgesia to enhance recovery after coronary artery bypass grafting: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Patient-Controlled Analgesia in ICU: A Scoping Review.Journal of personalized medicine · 2026Review
- Perioperative Flurbiprofen Axetil Administration and Acute Kidney Injury After Non-Cardiac Surgery: A Retrospective Cohort Study.Drug design, development and therapy · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients who undergo cardiac surgery often face postoperative pain and potential cognitive issues. Multimodal analgesia may address these problems. We hypothesized that multimodal analgesia can reduce opioid use and improve cognitive recovery.
aimTo investigate the effects of multimodal analgesia on postoperative opioid consumption and cognitive recovery in patients who underwent cardiac surgery.
methodsA prospective, randomized controlled trial at General Hospital from January 2020 to April 2023 recruited a total of 150 adult patients who underwent elective cardiac surgery. The patients were randomly divided into two groups. Group A had patient-controlled intravenous analgesia with sufentanil and flurbiprofen axil. Group B had flurbiprofen axil and paravertebral nerve block. Data were analyzed with appropriate statistical methods.
resultsGroup B had lower postoperative patient-controlled intravenous analgesia drug consumption (2.21 mL/hour
conclusionMultimodal analgesia with paravertebral nerve block and flurbiprofen axil reduces opioid use and improves cognitive outcomes in patients who underwent cardiac surgery.
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