ArticleWorld journal of gastroenterology2025
Effect of electroacupuncture combined with Tuina therapy on gut microbiota in patients with knee osteoarthritis.
Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Focus on necroptosis: its role in the pathogenesis and therapeutic potential of osteoarthritis.Frontiers in immunology · 2026Review
- Therapeutic effect of modified meridian-guided acupoint pressing on lumbar facet joint osteoarthritis: an integrated microbiomics and metabolomics analysis.Frontiers in medicine · 2026Article
- Gut microbiota and osteoarthritis: mechanisms and translation.Frontiers in immunology · 2026Review
- Non-Pharmacological Complementary and Alternative Therapies for Knee Osteoarthritis: A Scoping Review of Randomized Controlled Trials.Journal of pain research · 2026Review
- Mechanistic insights into gut microbiota dysbiosis in osteoarthritis based on the gut-joint axis.Frontiers in immunology · 2026Review
- The Gut-Joint Connection: Microbiome's Role in Rheumatic Disease.Archives of rheumatology · 2025Review
- Acupuncture modulates the microbiota-gut-brain axis: a novel therapeutic strategy for amnestic mild cognitive impairment.Frontiers in neuroscience · 2025Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKnee osteoarthritis (KOA) is a chronic condition characterized by joint pain and dysfunction, driven by aging and obesity. Research indicates that the gut microbiota significantly influences KOA, potentially affecting inflammation and disease progression through the gut-joint axis. Traditional treatments like non-steroidal anti-inflammatory drugs offer symptom relief but have adverse effects. Emerging therapies like electroacupuncture (EA) and Tuina (TN) have shown promise in alleviating pain and improving joint function by targeting the gut microbiota.
aimTo clarify the efficacy of EA with TN in treating KOA and its effect on gut microbiota regulation.
methodsSixty patients with KOA were allocated to EA or EA + TN (ET) group (
resultsThe ET group showed higher rates of "effective" and "markedly effective" outcomes. The VAS score of the ET group remained significantly lower than that of the EA group (
conclusionET outperforms EA alone in improving KOA pain, stiffness, and function, potentially
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