ArticleFrontiers in physiology2025
DGM-TOP: automatic identification of the critical boundaries in atrial tachycardia.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Role of interatrial connection ablation in re-entry dynamics: an in silico evaluation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Paired reentries maintain ventricular tachycardia: a topological analysis of arrhythmic mechanisms using the index theorem.Frontiers in network physiology · 2025Article
- Reentry-driven model of atrial fibrillation is maintained by paired reentries and terminated by strategic pairwise virtual ablation.Frontiers in physiology · 2025Article
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15 authors.
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Abstract
Introduction: In the latest research on topology in cardiac arrhythmia, it was demonstrated through a fundamental mathematical principle called the index theorem that reentry based atrial tachycardias (AT) are maintained by pairs of counter-rotating waves that are either complete or near-complete rotations. Each wave is centered around a different anatomical object that exhibits a non-zero index/topological charge, called a critical boundary. Interconnecting both critical boundaries with an ablation line terminates the tachycardia. Methods: This research focuses on the specific algorithms for calculating the index/topological charge of each anatomical boundary, called DGM-TOP. The algorithm used analyzes the electroanatomical map of the patient, extracting the nodes at each boundary. The index is then calculated for each boundary by sequentially summing the differences in local activation time and normalizing by the cycle length. Boundaries with a non-zero index are identified as critical boundaries. Results and discussion: Using this method, pairs of critical boundaries were consistently detected in 100% of the 578
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