ArticleUrology case reports2025
Serial evaluation of gonads of complete androgen insensitivity syndrome from birth to puberty: Is gonadectomy necessary?
Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
The timing of gonadectomy in patients with complete androgen insensitivity syndrome (CAIS) remains controversial due to concerns about the potential risk of malignancy. We report a rare case of CAIS diagnosed shortly after birth, prompted by a discrepancy between the karyotype identified through amniocentesis and the phenotype at birth. Early diagnosis allowed for longitudinal evaluation of the gonads from birth through puberty. Although gonadal tumors developed during puberty, histopathological examination revealed benign lesions. These findings suggest that, with careful monitoring, gonadectomy might have been safely deferred until adulthood in this patient.
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