SynthesisFrontiers in neurology2025
Effect of three rehabilitation methods combined with transcranial electromagnetic stimulation on post-stroke aphasia: a RCT network meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
4 authors.
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Abstract
Background: Stroke is a leading cause of death and disability worldwide, particularly in China, where it affects younger populations. Aphasia, a common post-stroke disorder, impairs language skills and occurs in 30-40% of stroke patients. Neuromodulation techniques like transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have shown promise in aphasia rehabilitation. Combining these methods with traditional treatments may improve recovery and shorten rehabilitation time. This study examines the effectiveness of these combined therapies in post-stroke aphasia (PSA) to inform clinical practice. Methods: Six databases, including PubMed, Embase, and Web of Science, were systematically searched, and 14 randomized controlled trials (RCTs) with 376 stroke patients were finally included. The outcome indicators were aphasia and quality of life related indicators. Net meta-analysis was performed using Stata 17.0 to assess the relative effectiveness of each combined intervention and to test the consistency of direct and indirect evidence. Results: In this study, a total of 14 randomized controlled trials (RCTs) involving 376 patients with stroke were included. For the primary outcome metrics, SLT was most effective in improving Naming (SMD = 1.09, 95% CI [0.16, 2.02], Conclusion: SLT and CSLT can effectively improve aphasia in stroke patients. It is recommended to prioritize their application in clinical rehabilitation. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42024611829.
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