Evidence map›Paper›PMID 40496056›Full record

ArticleJournal of molecular and cellular cardiology plus2025

Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants.

Tatiana Flisikowska, Björn Petersen, Giulia Mearini, Daniela Huber, Mayuko Kurome, Melanie Stoff, Saskia Schlossarek, Andrea Lucas-Hahn, Eckhard Wolf, Judith Montag and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tatiana FlisikowskaChair of Reproductive Biotechnology, Technical University of Munich (TUM), Munich, Germany.
Björn PetersenInstitute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Neustadt, Germany.
Giulia MeariniInstitute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Daniela HuberChair of Livestock Biotechnology, Technical University of Munich (TUM), Munich, Germany.
Mayuko KuromeGene Center and Department of Veterinary Sciences, Ludwig Maximilians University (LMU), Munich, Germany.
Melanie StoffDepartment of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
Saskia SchlossarekInstitute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Andrea Lucas-HahnInstitute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Neustadt, Germany.
Eckhard WolfGene Center and Department of Veterinary Sciences, Ludwig Maximilians University (LMU), Munich, Germany.
Judith MontagDepartment of Molecular and Cell Physiology, Hannover Medical School, Hannover, Germany.
Angelika SchniekeChair of Livestock Biotechnology, Technical University of Munich (TUM), Munich, Germany.
Lucie CarrierInstitute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is an autosomal-dominant disease caused by genetic variants in sarcomeric proteins, particularly in myosin binding protein C3 (

Indexed as

Base editingCRISPR/Cas9Gene editingHypertrophic cardiomyopathyMYBPC3MYH7Pig modelSomatic cell nuclear transfer

Identifiers

PMID40496056
PMCPMC12151660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.