Evidence map›Paper›PMID 40496035›Full record

ArticleIEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE International Conference on Nano/Micro Engineered and Molecular Systems2020

Bending Properties of Materials for Peripheral Nerve Interfaces.

Joshua E Woods, Elissa J Welle, Lei Chen, Julianna M Richie, Paras R Patel, Cynthia A Chestek

Abstract read
In one paragraph

Article in IEEE International Conference on Nano/Micro Engineered and Molecular Systems. IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Fabrication and Validation of Sub-Cellular Carbon Fiber Electrodes.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
    Article
  3. Article
  4. Sharpened and Mechanically Durable Carbon Fiber Electrode Arrays for Neural Recording.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joshua E WoodsDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA.
Elissa J WelleDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Lei ChenDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Julianna M RichieDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Paras R PatelDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Cynthia A ChestekDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA.

Funding

Highly-compliant Microneedle Arrays for Peripheral Nerve MappingOT2OD024907 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRUNS, TIMOTHY M., CHESTEK, CYNTHIA ANNE · 2017 to 2019
$1.9M
NIH HHS OT2 OD024907
6 · The paper itself

Abstract

Intrafascicular peripheral nerve interfaces (PNIs) with penetrating electrodes have the potential to chronically record from nerves on the scale of single axons. The small size and dynamic environment of peripheral nerves makes material selection important for these devices. In this work, we describe how the bending properties of common PNI electrode materials contribute to their effectiveness as self-inserting PNIs. First, tungsten, platinum-iridium, and carbon fiber wires are tested to assess their ability to survive repeated bending stresses when embedded in silicone. Next, carbon fiber wires are attached to a flexible circuit board encased in silicone to characterize how they survive stresses in prototype PNI devices. Finally, in order to validate experimental results, we use COMSOL to investigate the optimal thickness of the embedded silicone layer by simulating the stress distribution in carbon fiber wires on a flexible circuit board. Carbon fiber wires were shown to survive bending stresses better than tungsten and platinum-iridium wires. Physical testing and COMSOL modeling of carbon fiber prototype devices showed an optimal silicone thickness of 200

Identifiers

PMID40496035
PMCPMC12150231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.