ReviewThe mental health clinician2025
Evaluating the efficacy of blister packaging in improving medication adherence within psychiatry: A systematic literature review.
Review in The mental health clinician, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Perceived Barriers and Supports to Medication Adherence in Type 2 Diabetes: A Qualitative Study of Patients with and without a Zero-Dollar Copay Health Plan Benefit.Patient preference and adherence · 2026Article
- Qualitative study of blister pack use during buprenorphine low dose initiation.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Medication nonadherence is a prevalent and significant public health issue in the United States, particularly among patients with psychiatric disorders. Blister packaging medications is one of the most widely recognized and validated strategies for enhancing medication adherence. Given the paramount importance of adherence in psychiatry and the demonstrated effectiveness of blister packaging in chronic disorders, it is imperative to evaluate its effect in this context. Methods: A systematic literature review was conducted in PubMed and Google Scholar in May 2024 to identify relevant studies assessing the effect of blister packaging on medication adherence, health outcomes, and health care costs in psychiatry. Studies were included if they provided quantitative data on the effects of blister packaging on medication adherence in psychiatry. A meta-analysis was not performed due to differences in definitions of adherence in the included studies. Results: The review included 3 clinical studies and 1 cost-utility analysis (CUA). All 3 clinical studies demonstrated that blister packaging improved medication adherence rates. However, minimal data was available regarding its effect on clinical or patient-reported outcomes. The CUA found that blister packaging was dominant (less costly and more effective) compared with standard vial packaging. Discussion: The evidence presented in this review substantiates the positive effect for blister packaging in a psychiatric population. Nevertheless, due to the limited scope and size of the studies reviewed, further research with larger sample sizes is needed to fully assess the broader effect of blister packaging on clinical outcomes and health care costs within psychiatry.
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Registered trials
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