Evidence map›Paper›PMID 40495931›Full record

ReviewFrontiers in artificial intelligence2025

Deep learning architectures for influenza dynamics and treatment optimization: a comprehensive review.

Adane Adugna, Desalegn Abebaw, Abtie Abebaw, Mohammed Jemal

Abstract readReview
In one paragraph

Review in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adane AdugnaMedical Laboratory Sciences, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Desalegn AbebawMedical Laboratory Sciences, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Abtie AbebawMedical Laboratory Sciences, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Mohammed JemalDepartment of Biomedical Sciences, School of Medicine, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a major worldwide health concern, influenza still requires precise modeling of flu dynamics and efficient treatment approaches. Deep learning architectures are increasingly being applied to address the complexities of influenza dynamics and treatment optimization, which remain critical global health challenges. This review explores the utilization of deep learning methods, such as Long Short-Term Memory (LSTM) networks, Convolutional Neural Networks (CNNs), Generative Adversarial Networks (GANs), transformer architectures, and large language models (LLMs), in modeling influenza virus behavior and enhancing therapeutic strategies. The dynamic nature of influenza viruses, characterized by rapid mutation rates and the emergence of new strains, complicates the development of effective treatments and vaccines. In other words, the discovery of effective treatments and vaccines is severely hampered by the dynamic character of flu viruses, their fast rates of mutation, and the appearance of novel strains. Traditional epidemiological models often fall short due to their reliance on manual data interpretation and limited capacity to analyze large datasets. In contrast, deep learning offers a more automated and objective approach, capable of uncovering intricate patterns within extensive flu-related data, including genetic sequences and patient records. The application of deep learning to comprehend flu dynamics and improve treatment strategies is examined in this review paper. Moreover, this paper discussed relevant research findings, and future directions in leveraging deep learning for improved understanding and management of influenza outbreaks, ultimately aiming for more personalized treatment regimens and enhanced public health responses.

Indexed as

deep learning architecturesdeep learning modelsinfluenza dynamicsinfluenza predictiontreatment optimization

Identifiers

PMID40495931
PMCPMC12150876

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.