Evidence map›Paper›PMID 40495887›Full record

ReviewFrontiers in pharmacology2025

Unravelling the link between circadian clock genes and brain tumors: From pathological disruptions to potential therapeutic interventions.

Amirah Albaqami

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Amirah AlbaqamiDepartment of Clinical Laboratory Sciences, Turabah University College, Taif University, Taif, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circadian clock is present in nearly all tissues (including glial cells), which play crucial roles in brain functions and development. Circadian clock genes (CCGs) are responsible for regulating numerous cancer-associated biological mechanisms, including the regulation of cell cycle genes, apoptosis, and cell proliferation. A range of studies have already confirmed the potential link between brain tumors and CCGs, including

Indexed as

brain tumorscircadian clock genesglioblastoma multiformepathological disruptionspharmacological interventions

Identifiers

PMID40495887
PMCPMC12149115

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.