ArticleWorld journal of psychiatry2025
Relationship between uncertainty in illness and fear of progression among lung cancer patients: The chain mediation model.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Social support and self-efficacy mediate the link between health literacy and fear of disease progression in Chinese lung cancer patients.Scientific reports · 2026Article
- Psychological experiences of patients with Stanford type B aortic dissection during the preoperative waiting period: a qualitative study.BMC cardiovascular disorders · 2026Article
- Perceived social support as a mediator of the relationship between fear of progression and post-traumatic growth in lung cancer patients undergoing chemotherapy: a structural equation model analysis.Frontiers in psychiatry · 2026Article
- The impact of cancer information overload on negative emotions in newly diagnosed lung cancer patients: the mediating role of fear of progression and the moderating role of social support.Frontiers in psychiatry · 2025Article
- The impact of illness perception on quality of life in lung cancer chemotherapy patients: mediating effect of fear of progression.Frontiers in psychiatry · 2025Article
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6 authors.
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Abstract
backgroundUncertainty in illness (UI) and fear of progression (FoP) are significant psychological challenges for lung cancer patients. Coping styles and social support are critical mediators, influencing patients' ability to manage the emotional and psychological burden of UI and FoP. However, limited research has explored the chain mediation effect of these factors on the relationship between UI and FoP, particularly among Chinese lung cancer patients.
aimTo investigate the association between UI and FoP among patients with lung cancer.
methodsConvenience sampling was used to recruit inpatients diagnosed with lung cancer at a tertiary hospital in Changde City between November and December 2023. A total of 320 participants completed the Mishel Uncertainty in Illness Scale, Simplified Coping Style Questionnaire, Mandarin Chinese Version of the Medical Outcomes Study Social Support Survey, and Fear of Progression Questionnaire-Short Form. The chain mediation analysis was performed using the PROCESS macro to examine the relationships between the variables.
resultsThe results revealed that UI had a significant direct effect on FoP (effect = 0.224, 95%CI: 0.136-0.408). Additionally, three indirect pathways were identified: (1) Social support (effect = 0.128, 95%CI: 0.045-0.153); (2) Coping style (effect = 0.115, 95%CI: 0.048-0.157); and (3) Chain mediators involving social support and coping style (effect = 0.072, 95%CI: 0.045-0.120). The total indirect effect of the three mediation paths is 31.5%. These results confirm that social support and coping style significantly mediate the relationship between UI and FoP.
conclusionBased on cross-sectional data and a chain mediation model, this study explored the mechanisms between UI, social support, coping style, and FOP. Patients with lung cancer have higher levels of FOP, and the results of this study revealed a correlation between these four factors. Social support and coping style partially mediated the effects of UI on FOP, and there was a chain-mediating effect between UI and FOP. Programs designed to strengthen social support networks should also incorporate training to develop adaptive coping strategies, ultimately reducing FOP and improving overall quality of life.
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