ReviewCureus2025
Isoperistaltic Versus Antiperistaltic Side-to-Side Ileocolic Anastomoses After Right Colectomies: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparing access routes and anastomotic techniques for right-sided colonic resections: meta-analysis of randomized clinical trials.Surgical endoscopy · 2026Pooled it
- The effectiveness and safety of isoperistaltic versus antiperistaltic side-to-side ileocolic anastomosis in minimally invasive radical right hemicolectomy: a systematic review and meta-analysis.International journal of colorectal disease · 2026Pooled it
- Comparison of Intracorporeal Isoperistaltic and Antiperistaltic Anastomoses in Robotic-assisted Surgery for Right-sided Colon Cancer.Cancer diagnosis & prognosisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After right colectomy, ileocolic anastomoses can be configured as isoperistaltic (ISO) or antiperistaltic (ANTI), with the choice largely based on the surgeon's experience. This study aimed to evaluate these configurations regarding postoperative complications and operative outcomes. We searched PubMed, Scopus, and the Cochrane Central Register of Clinical Trials for studies published up to January 2025. Odds ratios (ORs) and mean differences (MDs), with 95% confidence intervals (CIs), were pooled using a random-effects model. Heterogeneity was assessed using the I² statistic, and analyses were conducted with R Software version 4.4.1. Twelve studies involving patients undergoing colorectal surgery were included, comparing ISO and ANTI ileocolic anastomoses. ISO was associated with a significantly earlier return of flatus (MD: -0.3 days; 95% CI: -0.6 to -0.1; p<0.01). No statistically significant differences were found in anastomotic leak (OR: 0.61; 95% CI: 0.29-1.28; p=0.189), postoperative ileus (OR: 1.47; 95% CI: 0.87-2.50; p=0.149), anastomotic bleeding (OR: 0.70; 95% CI: 0.20-2.49; p=0.582), surgical site infection (SSI) (OR: 0.91; 95% CI: 0.38-2.17; p=0.829), reoperation (OR: 0.92; 95% CI: 0.47-1.82; p=0.813), time to first stool (MD: -0.3 days; 95% CI: -0.7 to 0.1; p=0.19), anastomotic time (MD: -0.2 minutes; 95% CI: -1.9 to 1.4; p=0.79), blood loss (MD: -4.0 mL; 95% CI: -17.8 to 9.8; p=0.57), operative time (MD: 4.2 minutes; 95% CI: -3.0 to 11.3; p=0.25), hospital stay (MD: -0.7 days; 95% CI: -1.7 to 0.4; p=0.19), or 30-day mortality (OR: 0.85; 95% CI: 0.25-2.86; p=0.787). Based on our findings, ISO and ANTI ileocolic anastomoses demonstrated comparable postoperative complication rates and operative outcomes. However, ISO was associated with a faster return of bowel function, evidenced by earlier passage of flatus.
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Registered trials
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