Evidence map›Paper›PMID 40495515›Full record

ReviewBrain and behavior2025

Stroke in High-Altitude Areas.

Chuanxi Duan, Lijun Wu, Yuding Luo, Jiali Zhang, Pingchuan Liu, Fanzhou Ren, Junhao Li, Hai Xiong, Jian Wang

Abstract readReview
In one paragraph

Review in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chuanxi DuanNorth Sichuan Medical College, Nanchong, China.ORCID https://orcid.org/0009-0004-8449-7065
Lijun WuDepartment of Neurology, Fushun People's Hospital, Zigong, China.
Yuding LuoDepartment of Neurology, Ya'an People's Hospital, Ya'an, China.
Jiali ZhangDepartment of Neurology, Ya'an People's Hospital, Ya'an, China.
Pingchuan LiuDepartment of Neurology, the Affiliated Hospital, Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0009-0007-4045-9624
Fanzhou RenNorth Sichuan Medical College, Nanchong, China.
Junhao LiDepartment of Neurology, Ya'an People's Hospital, Ya'an, China.ORCID https://orcid.org/0009-0003-0396-5246
Hai XiongDepartment of Neurology, Ya'an People's Hospital, Ya'an, China.
Jian WangDepartment of Neurology, Ya'an People's Hospital, Ya'an, China.ORCID https://orcid.org/0000-0001-7064-1194

Funding

Sichuan Provincial Health Commission Special Clinical Research Project 23LCYJ034The Chengdu Medical College-Ya'an People's Hospital Clinical Science Research Fund 24LHLNYX1-38The Sichuan Medical Science and Technology Innovation Research Association Project YCH-KY-YCZD2024-037The Sichuan Provincial Natural Science Foundation General Project 2025ZNSFSC0618
6 · The paper itself

Abstract

backgroundStroke poses a significant social and familial burden on populations worldwide. While research on stroke in low-altitude areas is extensive, there remains a considerable gap in stroke research in high-altitude regions.

methodsA computer-based search of PubMed and Google Scholar was conducted to retrieve literature on stroke in high-altitude areas. Cross-referencing was performed using available articles and other scientific search engines. Relevant studies on stroke in high-altitude regions were included in this review.

resultsA total of five review articles, two systematic reviews and meta-analyses, three cross-sectional studies, nine retrospective clinical studies (including case reports and case-control studies), one commentary, one letter, and three animal studies were included in this literature review. All data were sourced from high-altitude regions.

conclusionWe explored the contribution of environmental and individual factors in high-altitude areas to the occurrence and progression of stroke, and highlighted the current research advances in ischemic stroke, hemorrhagic stroke, post-stroke cognitive impairment in high-altitude regions, and flight-related stroke. In light of the current limitations in research on stroke in these areas, we propose feasible directions for future studies, aiming to provide insights for future research on stroke in high-altitude regions.

Indexed as

AltitudeStrokeAnimalsHumansflight‐associated strokehigh altitudepost‐stroke cognitive impairmentstroke

Identifiers

PMID40495515
PMCPMC12152270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.