Purinergic Receptor P2Y2 Activity Prevents DNA Damage in CCl
Erandi Velázquez-Miranda, Ana Patricia Juárez-Mercado, Esperanza Mata-Martínez, María Guadalupe Ramírez-Ledesma, Adriana González-Gallardo, María Eugenia Ramos-Aguilar, Olivia Vázquez-Martínez, Mauricio Díaz-Muñoz, Francisco G Vázquez-Cuevas
Article in Journal of cellular biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Erandi Velázquez-MirandaDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Ana Patricia Juárez-MercadoDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Esperanza Mata-MartínezDepartamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, CDMX, México.
María Guadalupe Ramírez-LedesmaDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Adriana González-GallardoUnidad de Proteogenómica, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
María Eugenia Ramos-AguilarDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Olivia Vázquez-MartínezDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Mauricio Díaz-MuñozDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.ORCID 0000-0002-9019-8246
Francisco G Vázquez-CuevasDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.ORCID 0000-0002-8248-332X
Funding
This study was supported by grants from SECIHTI (#CBF2023-2024-200 for F.G.V.C.) and PAPIIT-UNAM (#IN202121 for M.D.M. and #IN205223 for F.G.V.C.). Esperanza Mata Martínez and María Guadalupe Ramírez Ledesma are postdoctoral fellows funded by SECIHTI-México, 2023.
6 · The paper itself
Abstract
DNA damage is one of the key processes that underlie hepatic fibrosis, and its progression could lead to the development of neoplastic events and ultimately hepatocarcinoma. Tissue injury, including DNA damage, can involve the activation of purinergic signaling. It has been shown that P2Y2 receptor signaling is exacerbated during hepatic fibrosis. Little is known, however, about the roles played by P2Y2 receptor in the processes involved in fibrosis. In this study, we used CCl
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Purinergic Receptor P2Y2 Activity Prevents DNA Damage in CCl · full record | OpenQuestion