Evidence map›Paper›PMID 40495457›Full record

ArticleBrain and behavior2025

Association Between Education Levels and Sedentary Behavior With Depression Among US Adults.

Chun Yang, Tiankuo Gao, Yichen Zhang, Cuicui Feng, Kai Zhang

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Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Peripheral S-(PGJBMC psychiatry · 2026
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  3. Observational
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chun YangBeijing Anzhen hospital, Capital Medical University, Beijing, China.
Tiankuo GaoBeijing Anzhen hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0008-5821-1018
Yichen ZhangLongyan University, Longyan, China.
Cuicui FengBeijing Anzhen hospital, Capital Medical University, Beijing, China.
Kai ZhangLongyan University, Longyan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarlier studies have proposed the effect of education level and sedentary behavior (SB) on the incidence of depression in adults. However, the association between the combination of education level and SB and depression in adults has not yet been investigated.

methodsThis study population consisted of US adults (aged ≥18 years) who participated in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018. A multivariable logistic regression model was employed to assess the association between education level, SB, and depression.

resultsOf the 29,822 participants (weighted mean [SE] age, 47.9[0.2] years; 51.2% male) in our study cohort. Depression was negatively linked to the higher education level (adjusted OR = 0.68 [95% CI: 0.57-0.81], Model 4) and positively correlated to higher SB (adjusted OR = 1.58 [95% CI: 1.34-1.87]). The ORs [95% CIs] for depression were 1.40 [1.13-1.74], 1.68 [1.20-2.35], and 1.78 [1.42-2.22], respectively, among lower education groups sitting < 6 h a day (h/d), 6-8 h/d and ≥ 8 h/d compared with higher education/ sitting < 6 h/d groups (Model 3). Among participants with higher education, those who engaged in SB ≥ 8 h/d had a 1.53-fold [95% CI, 1.31-1.79] increased risk of depression compared with those who sat for <6 h/d (p < 0.0001; Model 4).

conclusionsA lower education level and prolonged SB are independently and jointly associated with an increased risk of depression. Interventions that aim to reduce SB, especially among those with lower educational levels and also among those with higher educational levels who sit for more than 8 h per day, may help reduce the prevalence of depression.

Indexed as

DepressionEducational StatusSedentary BehaviorAdultFemaleHumansMaleMiddle AgedNutrition SurveysRisk FactorsUnited Statesdepressioneducation levelNHANESsedentary behavior

Identifiers

PMID40495457
PMCPMC12152267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.