Evidence map›Paper›PMID 40495381›Full record

ArticlePlant communications2025

Geminiviral replication enhancer hijacks a negative regulator of cytokinin signaling to facilitate viral infection.

Liu-Ming Guo, Jing Li, Pan-Pan Qi, Ling Qing, Heng-Mu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liu-Ming GuoLaboratory of Virology, Innovation Center of Chinese Medicine Crops, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China; Chongqing Key Laboratory of Plant Disease Biology, College of Plant Protection, Southwest University, Chongqing 400716, China.
Jing LiLaboratory of Virology, Innovation Center of Chinese Medicine Crops, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Pan-Pan QiLaboratory of Virology, Innovation Center of Chinese Medicine Crops, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Ling QingChongqing Key Laboratory of Plant Disease Biology, College of Plant Protection, Southwest University, Chongqing 400716, China; Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Southwest University, Chongqing 400716, China; National Citrus Engineering Research Center, Southwest University, Chongqing 400712, China. Electronic address: qling@swu.edu.cn.
Heng-Mu ZhangLaboratory of Virology, Innovation Center of Chinese Medicine Crops, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China. Electronic address: zhhengmu@tsinghua.org.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Geminiviruses are widespread across the globe and cause devastating diseases in food and medicinal crops. Their C3 proteins have long been known to enhance viral replication; however, the underlying molecular mechanisms remain poorly understood. In this study, we show that transgenic plants overexpressing the C3 protein of tobacco curly shoot geminivirus (TbCSV) exhibit hypersensitive responses to cytokinin (CK) treatment, which largely restores the attenuated viral replication observed in the TbCSV C3 mutant (TbCSV

Indexed as

BegomovirusCytokininsGeminiviridaeNicotianaPlant DiseasesViral ProteinsVirus ReplicationPlant ProteinsPlants, Genetically ModifiedSignal TransductionCytokininsPlant ProteinsViral ProteinsCKcytokinin signalinggeminivirusesnegative regulator of CK signalingTAF12bTAF12b-KMD-RR moduleTATA-box binding protein-associated factor 12bviral replication enhancer

Identifiers

PMID40495381
PMCPMC12365827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.