Evidence map›Paper›PMID 40495155›Full record

ArticleHarm reduction journal2025

The impact of institutionalization on the effectiveness of harm reduction: a qualitative study using drug users' representations.

Nicolas Khatmi, Lionel Dany, Perrine Roux

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicolas KhatmiInserm, IRD, SESSTIM, Sciences Economiques & Sociales de La Santé & Traitement de L'Information Médicale, ISSPAM, Faculté de Médecine, Site Timone, Aix Marseille Université, 27 Bd Jean Moulin, 13385, Marseille Cedex 05, France. nicolas.khatmi@inserm.fr.
Lionel DanyLaboratoire de Psychologie Sociale (UR 849), Aix-Marseille Université, 29 Avenue Robert Schuman, 13621, Aix-en-Provence, France.
Perrine RouxInserm, IRD, SESSTIM, Sciences Economiques & Sociales de La Santé & Traitement de L'Information Médicale, ISSPAM, Faculté de Médecine, Site Timone, Aix Marseille Université, 27 Bd Jean Moulin, 13385, Marseille Cedex 05, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe French harm reduction (HR) model has been incorporated into health policies at the institutional level since 2004. To assess the effectiveness of this process, this article examines the representations of people who inject drugs (PWID) treated in care centers in France. In particular, it focuses on how they perceive themselves and their drug injection practices. METHODOLOGY: We conducted a qualitative study using semi-structured interviews with 24 PWID attending both low- and high-threshold care centers. Lexical analysis and advanced statistical methods, including hierarchical clustering and correspondence analysis, were employed to elucidate the intricate relationships between the language utilized, the characteristics of the participants, and the care context.

resultsThe analysis identified four lexical classes, which collectively represented 96.9% of the corpus. These were: economic aspects (C1), social relationships and stigma (C2), therapeutic and medical care (C3), and technical skills (C4) related to drug injection practices. Two principal factors of variability significantly influenced these classes. Factor 1 primarily distinguished the discourse of PWID according to their socio-economic status, forming a gradient from those in more precarious situations-who accessed low-threshold care centers-to those with greater social stability-who accessed high-threshold care centers. Factor 2 highlighted the influence of temporal markers on discourse, particularly the period of drug injection initiation. This factor reveals a pronounced contrast between participants who initiated injection prior to the 2000s and those who began during or after the 2000s.

conclusionOur results demonstrate that PWID's experiences and perceptions were shaped not only by their socio-demographic characteristics but also by their social context, particularly the type of care center they attended. This study's findings reveal the limitations of the institutionalized HR model in the French healthcare system and advocate the development of a community-based approach to HR that aligns with its original principles.

Indexed as

Drug UsersHarm ReductionInstitutionalizationSubstance Abuse, IntravenousAdultFemaleFranceHumansMaleMiddle AgedQualitative ResearchSocial StigmaFranceHarm reductionLow thresholdPeople who inject drugsPublic health policySocial representations

Identifiers

PMID40495155
PMCPMC12150433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.