Evidence map›Paper›PMID 40495081›Full record

ArticleWorld journal of urology2025

Impact of transurethral resection of bladder tumors on sexual function and quality of life using ePROMs in patients with bladder cancer- a prospective cohort study.

H S Menold, B Gruene, J Koenig, M Lenhart, F Waldbillig, K F Kowalewski, M S Michel, M C Kriegmair, M Neuberger, F Wessels

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

H S MenoldDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. hanna.menold@umm.de.ORCID http://orcid.org/0009-0006-7815-0676
B GrueneDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
J KoenigClinic and Polyclinic for Child and Adolescent Psychiatry, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
M LenhartDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
F WaldbilligDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
K F KowalewskiDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
M S MichelDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
M C KriegmairDepartment of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
M Neuberger *Department of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
F Wessels *Department of Urology and Urosurgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe impact of transurethral resection of bladder tumors (TURBT) on patients' quality of life (QoL) and sexual function is underrepresented in the literature. Therefore, this study aimed to evaluate sexual function and QoL following TURBT, using electronic patient reported outcome questionnaires (ePROMs).

methodsPatients undergoing TURBT were surveyed using a digital ePROM system (Heartbeat Medical). Sexual function and QoL were assessed using the Male/Female LUTS Sexual Function module (ICIQ-MLUTSsex/FLUTSsex) at 3, 6 and 12 months postoperatively and the EORTC QLQ-NMIBC 24. Linear mixed-effects models were used to identify influencing factors, adjusting for baseline. Repeated measures ANOVA tested differences in domain scores over time.

results197 patients completed the survey, of whom 77% (n = 151) were men. Based on the ICIQ-MLUTSsex sexual function was significantly impaired at 3, 6 and 12-months postoperatively compared to baseline (p = 0.005; p = 0.004; p = 0.017). Age was the strongest factor for reduced male sexual function (ICIQ-MLUTSsex and QLQ-NMIBC24: p < 0.001). Subdomain analysis revealed negative effects on ejaculation (p = 0.044) and urinary symptoms (p = 0.031) up to 6 months. No differences were observed for the female population.

conclusionTURBT may result in long-term impairment of sexual function in male patients, whereas no such effect was observed in female patients within this cohort.

Indexed as

CystectomyPatient Reported Outcome MeasuresPostoperative ComplicationsQuality of LifeSexual Dysfunction, PhysiologicalUrinary Bladder NeoplasmsAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesBladder cancer; urinary bladder neoplasmsPatient-reported outcome measurementsQuality of lifeSexual functionTURB

Identifiers

PMID40495081
PMCPMC12152061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.