ReviewSports medicine - open2025
Overlaps of Skeletal Muscle Fatigue and Skeletal Muscle Damage: The Muscle Injury Continuum.
Review in Sports medicine - open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Improved muscle recovery after omega-3 supplementation is associated with increased oxylipin availability.Scientific reports · 2026Trial
- Acute ingestion of snake fruit jelly improves glycemic response, enhances endurance performance and antioxidant defense, and reduces inflammatory markers in healthy adults.Journal of the International Society of Sports Nutrition · 2025Trial
- Skeletal Muscle Redox Signaling in Health and Disease: From Molecular Mechanisms to Therapeutic Exercise Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- [Research on a muscle fatigue quantification based on an improved critical power model].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
- Muscle, Neuromuscular, and Cardiac Damage in Trail Running: A Systematic Review.Muscles (Basel, Switzerland) · 2026Review
- Artificial intelligence and sports genomics: advancing precision sports science and athletic performance.Frontiers in sports and active living · 2026Review
- Are three recovery days enough? Elevated match day creatine kinase levels under congested schedules in youth soccer.Biology of sport · 2026Article
- Prevalence and associated factors of pickleball-related injuries among Korean recreational players: a multi-tournament cross-sectional study.Frontiers in public health · 2026Article
- Skeletal muscle dysfunction induced by cancer immunotherapy: mechanistics insights and surgical implications.Frontiers in immunology · 2026Review
- Nonlinear association between physical fitness and sports injury risk among Chinese high school students: a cross-sectional study.BMC public health · 2025Article
- Kinetics of Serum Myoglobin and Creatine Kinase Related to Exercise-Induced Muscle Damage andJournal of functional morphology and kinesiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMuscle fatigue has long been identified as a potential risk factor for muscle overuse injuries, frequently occurring due to rapid eccentric contractions. Traditionally, muscle fatigue was thought to arise mainly to metabolic stress, whereas muscle damage was considered a consequence of mechanical overload. However, this binary approach fails to capture the complex physiological mechanisms, including prolonged-force depression, enzyme leakage or inflammatory responses, which overlap between both entities. MAIN TEXT: This narrative review synthesizes evidence regarding physiological and mechanical overlaps between muscle fatigue and muscle damage. It elaborates on the concept of a muscle injury continuum, including forms of muscle fatigue, possibly leading to mechanical tissue damage, and potentially culminating in severe muscle injuries. Additionally, the relevance of the overlaps for load monitoring and injury prevention in professional sports are discussed.
conclusionUnderstanding and recognizing the interplay between muscle fatigue and muscle damage is crucial for developing individualized prevention strategies, minimizing injury risk, and enhancing performance. This comprehensive approach is vital for improving load management and ensuring the long-term health and efficiency of athletes.
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Registered trials
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