Evidence map›Paper›PMID 40495063›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2025

Blood pressure management during cardiac surgery: a survey of Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons.

Karen Zhao, Renée Fournier, Kevin Kennedy, Hilary P Grocott, Emilie Belley-Côté, Matthew Cameron, Richard P Whitlock, C Scott Brudney, Allison M Janda, Eric Jacobsohn and 5 more

Abstract read
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Blood pressure management in cardiac surgery: how low can you go?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karen ZhaoFaculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Renée FournierFaculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Kevin KennedySchool of Population and Public Health, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
Hilary P GrocottDepartment of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Emilie Belley-CôtéPopulation Health Research Institute, Hamilton, ON, Canada.
Matthew CameronDepartment of Anesthesia, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Richard P WhitlockPopulation Health Research Institute, Hamilton, ON, Canada.
C Scott BrudneyDepartment of Anesthesiology, Perioperative and Pain Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Allison M JandaDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Eric JacobsohnDepartment of Anesthesiology, Perioperative and Pain Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
C David MazerDepartment of Anesthesia and Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
François LamontagneDepartment of Anesthesiology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Christie SmithDepartment of Clinical Perfusion, Trillium Health Centre, Mississauga, ON, Canada.
Gordon GuyattDepartment of Health Research Methods, Evidence, and Impact (HEI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Jessica SpencePopulation Health Research Institute, Hamilton, ON, Canada. jessica.spence@phri.ca.ORCID 0000-0003-1267-9455

Funding

PHEnylephrine versus NOrepinephrine in Major NONcardiac surgery (PHENOMeNON): Foundational Studies for a Pragmatic Randomized Clinical Trial.K23HL166685 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Allison Mary Janda · 2023 to 2026
$689k
NHLBI NIH HHS K23 HL166685
6 · The paper itself

Abstract

purposeClinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons. We sought to solicit information to inform a trial evaluating the blood pressure management approach on outcomes after cardiac surgery.

methodsWe iteratively developed a survey assessing the lowest and highest blood pressures respondents would target, the narrowest feasible blood pressure range to achieve, the range of blood pressure observed in clinical practice, and factors influencing targeted blood pressure before, during, and after cardiopulmonary bypass (CPB). We contacted leads from every Canadian hospital providing cardiac surgery to distribute the survey via a computerized link. We used a modified Dillman approach to optimize response rate. Responses were analyzed descriptively.

resultsOf 819 clinicians surveyed, 532 (65%) responded. Respondents' lowest pooled mean arterial pressure (MAP) target, presented as mean (standard deviation [SD]), was 59 (6) mm Hg before CPB, 55 (7) mm Hg during CPB, and 60 (5) mm Hg after CPB. Respondents' highest pooled MAP target, presented as mean (SD), was 92 (10) mm Hg before CPB, 84 (7) mm Hg during CPB, and 75 (6) mm Hg after CPB. The narrowest feasible MAP range, presented as mean (SD), all respondents believed could be achieved was 19 (7) mm Hg before CPB, 16 (7) mm Hg during CPB, and 20 (7) mm Hg after CPB.

conclusionsThe responses to our survey support the clinical acceptability of a trial examining blood pressure target thresholds at the extreme ends of the range recommended by existing guidelines and the feasibility of maintaining blood pressure within a narrow target range.

Indexed as

Blood PressureCardiac Surgical ProceduresAnesthesiologistsCanadaCardiopulmonary BypassHumansSurgeonsSurveys and Questionnairesblood pressurecardiac surgerysurvey

Identifiers

PMID40495063
PMCPMC12723998

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.