Evidence map›Paper›PMID 40495045›Full record

ArticleEndocrine2025

Geriatric status features of type 2 diabetes patients over 65: subanalysis of the EVKALIPT study.

Ekaterina N Dudinskaya, Natalia M Vorobyeva, Julia S Onuchina, Kristina O Chepygova, Lubov V Machekhina, Yulia V Kotovskaya, Olga N Tkacheva

Erratum issuedAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effect of manual diaphragmatic release on ventilatory function and functional capacity in elderly type 2 diabetic women: A randomised controlled trial.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ekaterina N DudinskayaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0000-0001-7891-6850
Natalia M VorobyevaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0000-0002-6021-7864
Julia S OnuchinaRussian Gerontology Research and Clinical Center, Moscow, Russia. onuchina90@list.ru.ORCID 0000-0002-0556-1697
Kristina O ChepygovaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0009-0006-9764-8445
Lubov V MachekhinaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0000-0002-2028-3939
Yulia V KotovskayaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0000-0002-1628-5093
Olga N TkachevaRussian Gerontology Research and Clinical Center, Moscow, Russia.ORCID 0000-0002-4193-688X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough type 2 diabetes mellitus (T2DM) is common among elderly patients, there are no large studies examining the geriatric status of patients with T2DM.

aimTo study the characteristics of geriatric status in patients with T2DM aged ≥ 65 years. MATERIALS AND

methodsThe multicenter EVKALIPT study conducted in 11 constituent entities of the Russian Federation included 4308 patients aged 65-107 years (mean age 78 ± 8 years), who were divided into two groups: with T2DM (n = 935) and without T2DM (n = 3360). All participants underwent a comprehensive geriatric assessment: a survey (step 1) and a physical examination (step 2).

resultsThe prevalence of type 2 diabetes was 21.8% (n = 935), predominantly in patients aged 65-74 years. The comprehensive geriatric assessment showed that changes in the geriatric status are more pronounced in T2DM, namely: lower basic activity in everyday life and a lower total score on the Short Physical Performance Battery (SPPB); slower walking speed; lower handgrip strength in women; worse health self-assessment score, higher total score on the geriatric depression scale (GDS-15) and on the questionnaire "Age is not a hindrance;" more pronounced pain syndrome; and the use of a greater number of assistive devices per patient was noted. Geriatric syndromes (GS), which were detected more often in the group with T2DM in comparison without T2DM were: chronic pain syndrome (91 vs 86%, p < 0.001), frailty (67 vs 62%, p = 0.005), basic dependence in everyday life (67 vs 60%, p < 0.001), depression (52 vs 47%, p = 0.004), urinary incontinence (51 vs 44%, p < 0.001), falls (34 vs 30%, p = 0.004%), and pressure ulcers (3.3 vs 2%, p = 0014). Regression analysis demonstrated that T2DM is associated with an increased risk of developing such GS as basic dependence of patients in everyday life, frailty syndrome, pressure ulcers, chronic pain, depression (odds ratio from 1.19-1.78).

conclusionGeriatric status was worse in patients with T2DM than in those without T2DM. It has been demonstrated that T2DM adversely affects the physical performance of patients aged 65 years and older. HIGHLIGHTS: To study the characteristics of geriatric status in patients with T2DM aged ≥ 65 years. T2DM was associated with geriatric syndromes due to worse performance status in patients aged ≥ 65 years. In routine clinical practice, it is necessary to identify geriatric syndromes in patients with T2DM. This will foster patient-centered approach, which undoubtedly contributes to improving the quality of life of elderly patients with T2DM.

Indexed as

Diabetes Mellitus, Type 2Geriatric AssessmentActivities of Daily LivingAgedAged, 80 and overDepressionFemaleHand StrengthHumansMalePrevalenceRussiaBasic activity in everyday lifeComprehensive geriatric assessmentGeriatric syndromesOlder peopleShort physical performance batteryType 2 diabetes mellitus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.