Evidence map›Paper›PMID 40494966›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

National trends and complications in the surgical management of diffuse idiopathic skeletal hyperostosis (DISH).

Alejandro Pando, Yaxel Levin-Carrion, Caryn J Ha, Drew Thibault, Marvens Jean, Ahmed Sabra, Daniel Ortega, Kevin Kwan, Hai Sun

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Association of diffuse idiopathic skeletal hyperostosis with postoperative outcomes following surgery for degenerative lumbar spine disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Alejandro PandoDepartment of Neurological Surgery, Rutgers New Jersey Medical School, Rutgers Robert Wood Johnson Medical School, NJ, USA. ap1611@njms.rutgers.edu.
Yaxel Levin-CarrionRutgers New Jersey Medical School, Newark, NJ, USA. yl1177@njms.rutgers.edu.
Caryn J HaRutgers New Jersey Medical School, Newark, NJ, USA.
Drew ThibaultLiberty University College of Osteopathic Medicine, Lynchburg, VA, USA.
Marvens JeanRutgers New Jersey Medical School, Newark, NJ, USA.
Ahmed SabraRutgers New Jersey Medical School, Newark, NJ, USA.
Daniel OrtegaColumbia University Irving Medical Center, New York Presbyterian-Och Spine Hospital, New York, NY, USA.
Kevin KwanDepartment of Neurological Surgery, RWJ Barnabas, Rutherford, NJ, USA.
Hai SunDepartment of Neurological Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory disorder characterized by calcification and ossification of ligaments and entheses of the spine. Limited literature exists on the characteristics, complications, and outcomes of patients undergoing different surgical approaches for DISH. This study aims to identify patient factors associated with postoperative complications and predictors of surgical approach.

methodsThe 2016 to 2021 National Inpatient Sample (NIS) was used to identify adult inpatients with a primary diagnosis of DISH. From this cohort, those who underwent spine surgery were further identified and subdivided based on the surgical approach and analyzed for demographics, comorbidities, and other patient characteristics to identify associations and trends.

resultsAmong 5,322 DISH patients, surgical intervention increased from 9.0% in 2016 to 21.5% in 2021. Of 1,560 surgical patients, PDF was more common (68.3%), followed by ADF (18.0%) and APDF (8.7%). ADF had the shortest time to treatment (0.8 ± 2.1 days, p < 0.001), shortest hospital stay (6.0 ± 7.5 days, p < 0.001), and lowest costs ($147,525 ± 137,728, p < 0.001). APDF had the longest hospital stay (9.4 ± 10.6 days, p < 0.001) and highest costs ($361,124 ± 345,692, p < 0.001). Neurologic complications were highest in APDF (14.1% vs. 3.9%, p < 0.001), while ADF had higher dysphagia/aspiration pneumonia rates (35.6% vs. 10.6%, p < 0.001). ADF patients were more likely to be discharged home (55.9% vs. 26.7% PDF, p < 0.001), whereas PDF and APDF patients were more often discharged to skilled nursing/rehabilitation facilities. Independent predictors for PDF included older age (OR: 1.02, p < 0.01) and thoracic spine pathology (OR: 9.31–18.48, p < 0.05).

conclusionSurgical approach in DISH patients influences outcomes. ADF demonstrates advantages in recovery and costs but increases dysphagia risk. Awareness of surgical risks can improve patient selection and outcomes.

Indexed as

Hyperostosis, Diffuse Idiopathic SkeletalPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedUnited StatesAnkylosing hyperostosisAnterior longitudinal ligamentDiffuse Idiopathic Skeletal Hyperotosis (DISH)Forestier DiseaseForestier’s DiseaseManagementNeurosurgeryOssificationPosterior longitudinal ligamentSpine SurgerySurgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.