Observational studyPediatric research2026
Severity of respiratory syncytial virus through the COVID-19 pandemic among infants aged ≤2 months: a secondary analysis of the IRIDE cohort study.
Observational study in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Delayed Seasonality but Consistent Age Burden: RSV Epidemiology Pre-, During, and Post-COVID-19 Pandemic on the Kenyan Coast (2008-2026).Open forum infectious diseases · 2026Article
- Crimean-Congo Hemorrhagic Fever in Children: Secondary Hemophagocytic Lymphohistiocytosis and Time-course of Biomarkers in a Single-Center Cohort (2019-25).Journal of tropical pediatrics · 2026Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThrough the SARS-CoV-2 pandemic the severity of RSV infection increased among children, but little is known about its evolution among infants ≤60 days of life (DOL).
methodsMulticenter observational retrospective study conducted in 27 hospitals in Lombardy, Italy, comparing outcomes of infants (≤60 DOL) hospitalized with RSV bronchiolitis during 4 seasons: 2018-2019 (pre-pandemic period), 2020-2023 (pandemic seasons).
result1816 infants were included. Multivariable regressions showed that the need and length of O
conclusionOutcomes of RSV bronchiolitis among infants ≤60 DOL were slightly affected by COVID-19 pandemic. The impact was less significant among neonates. Breast milk components might have mitigated the negative effect of COVID-19 on RSV severity in neonates. CATEGORY OF STUDY: Clinical and population study. IMPACT: Outcomes of RSV bronchiolitis among infants ≤60 days of life (DOL) were slightly affected by COVID-19 pandemic. Neonates (≤28 DOL) in our cohort seem to have significantly better outcomes than older infants (29-60 DOL). To date no data is available on the effects of non-pharmacological interventions on the diffusivity and severity of RSV infection in infants aged ≤60 DOL, the population at highest risk for RSV-related complications Breast milk and its innate immune components may have played an important role as protective factors against RSV respiratory infections during the first month of life.
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