ArticleDiabetic medicine : a journal of the British Diabetic Association2025
Variation in effectiveness of the NHS Diabetes Prevention Programme in people diagnosed with non-diabetic hyperglycaemia by age, sex, BMI, and deprivation: A matched cohort analysis of 69,801 people.
Article in Diabetic medicine : a journal of the British Diabetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Variation in effectiveness of the NHS Diabetes Prevention Programme in people diagnosed with non-diabetic hyperglycaemia by age, sex, BMI, and deprivation: A matched cohort analysis of 69,801 people.Diabetic medicine : a journal of the British Diabetic Association · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
aimsThe NHS Diabetes Prevention Programme (DPP) is a behaviour-change programme aimed at adults diagnosed with non-diabetic hyperglycaemia (NDH), who are at higher risk of developing type 2 diabetes mellitus (Diabetes). This paper explores the heterogeneity in the effectiveness of the DPP by age, sex, BMI, and practice location deprivation (IMD).
methodsMatched cohort analysis with random-effects parametric survival models, evaluating the association between referral to the DPP and conversion to diabetes, with interactions fitted for age, sex, BMI, and IMD.
results18,470 patients referred to the programme were matched to 51,331 controls. None of the interactions of patient characteristics with referrals were statistically significant. For women, the difference in the HR of conversion to diabetes, compared to men, was HR = 0.94 (95% CI: 0.81, 1.08, p = 0.38); For those aged [18-34], HR = 0.79 (95% CI: 0.34, 1.84, p = 0.58) and aged [75-84] HR = 0.86 (95% CI:0.66, 1.12, p = 0.26) compared to those aged [55-64]. The HR for conversion was 0.88 (95% CI:0.62, 1.26, p = 0.49) for those with a BMI ≥ (25-29.9) kg/m
conclusionsThe DPP was effective in reducing conversion rates from NDH to diabetes as shown in our previous study results. The intervention appeared to be similarly effective by age, sex, BMI, and deprivation.
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