Evidence map›Paper›PMID 40494066›Full record

ArticleThe Journal of surgical research2025

R01 Funding for Surgeons; What Are the Key Factors for Success?

Shadin Ghabra, Lindsay A Demblowski, Carolina Larrain, Hyoyoung Choo-Wosoba, Martha A Zeiger

Abstract read
In one paragraph

Article in The Journal of surgical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shadin GhabraSurgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Lindsay A DemblowskiOffice of Surgeon Scientist Programs, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Carolina LarrainSurgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Hyoyoung Choo-WosobaOffice of Collaborative Biostatistics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Martha A ZeigerOffice of Surgeon Scientist Programs, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: martha.zeiger@nih.gov.

Funding

Training and Development of Outstanding Surgeon ScientistsZIEBC011992 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ZEIGER, MARTHA · 2020 to 2024
$9.6M
Intramural NIH HHS ZIE BC011992
6 · The paper itself

Abstract

introductionRecent studies report a decrease in R01 grants awarded to surgeon-scientists compared to nonsurgeons. We determined the key factors associated with a successful R01 grant application for surgeon-scientists.

methodsSurgeon-scientist principal new investigators (PIs) who applied for an R01 grant during fiscal years (FY) 2018-2023 were identified using an National Institutes of Health internal data platform. Individual and multivariable analyses were performed for gender, degree (medical degree with or without PhD), previous research training grants (F32 and T32), same faculty and clinical training institution, previous mentored funding (K08, K23, and K99), and Hirsch index for awarded and nonawarded PIs. Preliminary analyses were conducted to explore associations between the R01 award and each variable followed by a multiple logistic regression analysis.

resultsOf 310 (35.1%) R01-awarded surgeon PIs, there was no statistical difference in the proportion of awarded men (n = 203, 34.5%) versus women (n = 107, 36.5%) PIs (P = 0.55). The results indicated a strong likelihood of success for PIs with a PhD degree (univariable P = 0.007; odds ratio (OR) = 1.39, P = 0.042 by the logistic model), for those who were previously on an F32 or T32 training grant (P = 0.008; OR = 1.51, P = 0.025), and were previously awarded a mentored-career grant (K08, K23, or K99) (P < 0.0001; OR = 2.72, P < 0.0001). In contrast, remaining at the same organization as their surgical training (P = 0.069; OR = 1.27, P = 0.109), and an h-index ≥40 (P = 0.183; OR = 1.34, P = 0.184) were not indicators of success.

conclusionsVariables identified for successfully transitioning to independent R01 as first investigator surgeon scientist funding include holding a PhD degree, a previous research training grant, and a previous mentored career award.

Indexed as

Biomedical ResearchResearch PersonnelResearch Support as TopicSurgeonsFemaleHumansMaleNational Institutes of Health (U.S.)United StatesNew investigatorNIH fundingNIH grantR01 grantSurgeon-scientistSurgical research

Identifiers

PMID40494066
PMCPMC12403965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.