ArticleInterdisciplinary cardiovascular and thoracic surgery2025
Microplastics in cardiopulmonary bypass: quantification and characterization of particles across systems.
Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Micro- and Nanoplastics in Cardiovascular Toxicology: Human Tissue Detection, Clinical Phenotypes, and Adverse Outcome Signals.Cardiovascular toxicology · 2026Review
- Micro- and Nanoplastics as Emerging Cardiovascular Risk Factors: A Systematic Review.Journal of xenobiotics · 2026Review
- Microplastic in perfusion: the hidden risk and how to address it.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study determines the microplastic (MP) levels, dimension, shape, and chemical composition generated from conventional cardiopulmonary bypass and minimally invasive extracorporeal circulation (MiECC) circuits.
methodsIn vitro conventional and MiECC circuits, mimicking realistic setups with 2 L of Hartmann's solution were run for 90 min (n = 3 circuit runs each), filtered, and analysed using micro-Fourier transform infrared spectroscopy alongside procedural blanks (n = 5).
resultsConventional circuits produced 60.4 ± 7.6 MPs L-1h-1 (77.0% of the total particles). MiECC circuits produced 48.4 ± 31.3 MPs L-1h-1 (45.3% of total particles). MP levels in each circuit type were significantly elevated compared with procedural blank (n = 5) samples (5.6 ± 10.4 MPs L-1h-1) but did not differ with respect to the other. Twenty different MP polymer types were detected whereby polydimethyl siloxane, poly(decyl methacrylate), and poly(N-butyl methacrylate) represented the most MPs within conventional circuits. For MiECC, the most abundant were polypropylene, polyethylene, and polyamide. Average MP lengths differed significantly: 93.5 ± 98.6 µm (conventional) versus 62.0 ± 54.4 µm (MiECC) (P < 0.001), although widths did not differ. Film particles (48.2%) were the predominant shape for conventional circuits and fragments (50.5%) for MiECC.
conclusionsSignificant levels of MP particles were produced across the two systems. Future studies can determine the time points at which they are produced in machine use, to mitigate their production, as well as inform cell/tissue culture investigations into the clinical significance of their introduction into patients undergoing cardiac surgery.
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