ArticleMagnetic resonance in medicine2025
Correcting pulse duration effects in the diffusional kurtosis of the multi-compartment Kärger model.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Monte Carlo Assessment of Accuracy for Mean Kärger Model Water Exchange Rate Estimates From Diffusional Kurtosis Time Dependence.NMR in biomedicine · 2026Article
- Correcting pulse duration effects in the diffusional kurtosis of the multi-compartment Kärger model.Magnetic resonance in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
purposeTo demonstrate a method of reducing pulse duration effects for the diffusional kurtosis of the multi-compartment Kärger model (KM) as estimated with a Stejskal-Tanner DWI sequence. THEORY AND
methodsAn effective diffusion time is introduced that corrects errors in the apparent diffusional kurtosis arising from a nonzero pulse duration δ for the multi-compartment KM. The correction is exact to first order in the diffusion time Δ, and numerical calculations are used to assess how well it reduces pulse duration effects. Specifically, for the two-compartment KM, the deviations of the apparent kurtosis obtained with the Stejskal-Tanner sequence from the exact kurtosis are calculated for the full range of δ and Δ, and similar calculations are performed for the deviation in the derivative of the kurtosis with respect to Δ. For the general multi-compartment KM, upper bounds on the maximum magnitude of the deviations are determined. Application of the correction to estimation of intercompartmental exchange rates is illustrated with several examples.
resultsFor the two-compartment KM, the correction reduces the deviation of the apparent kurtosis and its time derivative for most values of δ and Δ. For the general multi-compartment KM, the maximum deviation magnitude, relative to the initial kurtosis, is 2.26% for the uncorrected kurtosis and 0.57% after correction. The correction reduces the maximum deviation magnitude of the derivative from 46% to less than 1%.
conclusionPulse duration effects for the kurtosis of the multi-compartment KM can be strongly suppressed by applying the effective diffusion time correction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.