ArticleAngewandte Chemie (International ed. in English)2025
Biosynthesis of the Red Algal Diterpene Peyssonnosol in Bacteria.
Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Article
- Mechanistic Characterisation of Bacterial Terpene Synthases from Chitinophagaceae Producing Marine-Type Diterpenes.Angewandte Chemie (International ed. in English) · 2025Article
- Biosynthesis of the Red Algal Diterpene Peyssonnosol in Bacteria.Angewandte Chemie (International ed. in English) · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Two diterpene synthases (DTSs) for peyssonnosol and peyssonnosol B were discovered in bacteria. Their enzyme mechanisms were investigated through isotopic labelling experiments, density functional theory (DFT) calculations and site-directed mutagenesis, yielding biosynthetically related molecules that gave important insights into the terpene cyclisation cascade. In the present case, several mechanisms in line with the isotopic labelling experiments could be formulated. Only an extended experimental approach in combination with computational chemistry ultimately resulted in a refined mechanistic model.
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Registered trials
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