SynthesisSleep & breathing = Schlaf & Atmung2025
Continuous positive airway pressure treatment for sleep apnea in elderly patients systematic review and meta-analysis.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Obstructive Sleep Apneas and Cardiovascular Diseases.Clocks & sleep · 2026Review
- OSA in the aging population: Diagnostic and therapeutic considerations.Sleep medicine reviews · 2026Review
- Inflammation in Obstructive Sleep Apnea: A Global Bibliometric Perspective.Nature and science of sleep · 2025Article
- Adherence Patterns to Positive Airway Pressure in Elderly Patients With Obstructive Sleep Apnea.Open respiratory archivesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to review the literature of the last 10 years (published in 2015-2024), in order to evaluate the effect of continuous positive airway pressure (CPAP) treatment on obstructive sleep apnea (OSA) among the elderly. STUDY DESIGN AND
methodsWe conducted a meta-analysis of studies evaluating CPAP vs. usual care in patients more than 65 years with moderate to severe OSA. Our outcomes were changes in ESS (Epworth Sleepiness Scale), neurocognitive tests, Sleep-related Quality of Life (QSQ), and mortality.
resultsWe identified 229 studies from various databases, including 13 with 14,880 participants in our analysis. CPAP significantly was associated with improvement of sleepiness, anxiety and depression according to the effect size of -2.92, 0.2 and 0.35 respectively (CI: -3.82 to -2.03, 0.02 to 0.38, 0.03 to 0.67). The digit span and digit symbol were improved in the CPAP group by the small effect size of 0.19 and 0.24 respectively. (CI: 0.01 to 0.36, 0.06 to 0.41). Also mortality and diurnal symptoms were reduced with the moderate effect size of 0.64 and 0.61 respectively in the CPAP group. (CI: 0.52 to 0.75, 0.42 to 0.79).
conclusionCPAP significantly impacts daytime sleepiness, sleep-related quality of life, cognitive functions, and mortality in elderly individuals. Benefits are particularly evident in consistent users over four hours, especially regarding daytime sleepiness. Larger, well-structured randomized controlled trials involving compliant patients are crucial to provide robust evidence on CPAP effects in elderly populations, considering age-related comorbidities, cognitive performance, and neuropsychological issues.
Indexed as
Identifiers
40493304What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.