Evidence map›Paper›PMID 40493161›Full record

ReviewMolecular biotechnology2026

Tailoring Corynebacterium glutamicum for Sustainable Biomanufacturing: From Traditional to Cutting-Edge Technologies.

Eldin Kurpejović, Berna Sariyar Akbulut, Fatma Gizem Avci

Abstract readReview
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In one paragraph

Review in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eldin KurpejovićDepartment of Bioengineering, Faculty of Engineering, Marmara University, Istanbul, Türkiye.
Berna Sariyar AkbulutDepartment of Bioengineering, Faculty of Engineering, Marmara University, Istanbul, Türkiye.
Fatma Gizem AvciDepartment of Bioengineering, Faculty of Engineering and Natural Sciences, Üsküdar University, Istanbul, Türkiye. fatmagizem.avci@uskudar.edu.tr.ORCID http://orcid.org/0000-0001-6618-0487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the workhorse of industrial amino acid production, Corynebacterium glutamicum is the focus of this review, which provides a comprehensive overview of available techniques employed to engineer strains with desired traits. The review highlights both traditional and cutting-edge approaches with a brief introduction to the bacterium's physiology, serving as a foundation for understanding its metabolic capabilities and potential applications. Genome modulation techniques by contrasting traditional methods with CRISPR-based approaches, as well as transcription modulation strategies that enhance gene expression and metabolic flux, and high-throughput techniques that streamline strain development processes are summarized. Furthermore, the roles of artificial intelligence and machine learning in genetic engineering are explored, emphasizing their growing impact on strain development.

Indexed as

Corynebacterium glutamicumMetabolic EngineeringAmino AcidsArtificial IntelligenceBiotechnologyCRISPR-Cas SystemsGenetic EngineeringGenome, BacterialIndustrial MicrobiologyMachine LearningAmino AcidsCorynebacterium glutamicumGenome engineeringHigh-throughput analysisMachine learningTranscription modulation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.