Evidence map›Paper›PMID 40493153›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Frequency and severity response scales for pain and discomfort: psychometric insights from EQ-HWB.

Soumana C Nasser, A Simon Pickard, Jonathan L Nazari, Maja Kuharic

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Soumana C NasserDepartment of Pharmacy Practice, School of Pharmacy, Lebanese America University, Byblos, Lebanon.ORCID http://orcid.org/0000-0003-4202-7116
A Simon PickardDepartment of Pharmacy Systems, Outcomes and Policy, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-5645-7091
Jonathan L NazariDepartment of Pharmacy Systems, Outcomes and Policy, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-4758-7588
Maja KuharicDepartment of Pharmacy Practice, School of Pharmacy, Lebanese America University, Byblos, Lebanon. maja.kuharic@northwestern.edu.ORCID http://orcid.org/0000-0003-3696-9086

Funding

EuroQol Research Foundation 1811-RA
6 · The paper itself

Abstract

purposePain and discomfort are core dimensions of health-related quality of life. This study aimed to compare and evaluate the psychometric properties of frequency versus severity response scales in assessing pain and discomfort and determining their unique measurement contributions across different health conditions.

methodsThis secondary analysis utilized data from 1,008 participants derived through a dyadic study design of caregivers from the general population and their care recipients. Clinical data were based on self-reported health conditions. Pain and discomfort were assessed using the EQ-5D-5L and EQ-HWB experimental version. The analysis included Spearman's correlation, Shannon's indices, Item Response Theory (IRT), Differential Item Functioning (DIF), and ordinal logistic regression.

resultsPain frequency and severity items showed a strong correlation (rs=0.81, p<0.001), with similarly strong correlations across all pain and discomfort items (rs>0.5, p<0.001). Frequency scales demonstrated higher informativity than severity scales for both pain (H'=2.28, J'=0.98 vs H'=2.06, J'=0.89) and discomfort (H'=2.18, J'=0.94 vs H'=2.00, J'=0.86). IRT analysis revealed severity items had higher discrimination, while frequency items were more sensitive at lower trait levels. DIF analysis showed significant scale differences for pain (R2=0.24) but not discomfort (R2=0.001). Immunologic (OR=3.21) and musculoskeletal conditions (OR=2.65) were most strongly associated with pain frequency.

conclusionFrequency and severity scales capture distinct aspects of pain and discomfort. Frequency scales provide better informativity across trait levels, while severity scales offer superior discrimination at higher intensities. For a comprehensive assessment, both scales are valuable; however, frequency scales may be preferable in shorter instruments due to their broader measurement range and higher informativity.

Indexed as

PainPain MeasurementPsychometricsQuality of LifeAdultAgedCaregiversFemaleHumansMaleMiddle AgedReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesCARE-2BEQ-5DEQHWBHealth-related quality of lifePain assessmentPsychometric validationResponse scales

Identifiers

PMID40493153
PMCPMC12274242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.