Evidence map›Paper›PMID 40493098›Full record

ArticleTropical animal health and production2025

Effect of in ovo feeding of Centella asiatica leaf extract on hatchability, morphometric, visceral organs, intestinal morphology, and blood hematology parameters of Indonesian native chicks.

Arif Darmawan, Rantan Krisnan, Ida Nurul Fajri, Yuniartika Yuniartika, Marina Aisha Lusbiantoro, Ridho Kurniawan Rusli, Cecep Hidayat

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arif DarmawanDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, 16680, Bogor, Indonesia. arifdarmawan@apps.ipb.ac.id.ORCID http://orcid.org/0000-0001-5593-5469
Rantan KrisnanResearch Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Cibinong, Bogor, 16911, Indonesia.
Ida Nurul FajriDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, 16680, Bogor, Indonesia.
Yuniartika YuniartikaDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, 16680, Bogor, Indonesia.
Marina Aisha LusbiantoroDepartment of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, 16680, Bogor, Indonesia.
Ridho Kurniawan RusliDepartment of Nutrition and Feed Technology, Faculty of Animal Science, Universitas Andalas, 25175, Padang, Indonesia.
Cecep HidayatResearch Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Cibinong, Bogor, 16911, Indonesia.

Funding

Kementerian Keuangan Republik Indonesia No.473/IT3.D10/PT.01.03/P/B/2023
6 · The paper itself

Abstract

This study aimed to evaluate the effect of in ovo feeding of Centella asiatica leaf extract on hatchability, physical quality, blood hematology, visceral organs and immunity, and intestinal morphology of native chicks. A total of 300 fertile eggs were used in this study. This study used a completely randomized design with five treatments and six replicates, consisting of 10 fertile Sentul chicken eggs, each replicate. Treatments were uninjected eggs (P0), eggs injected with 0.5 ml PBS (P1), eggs injected with 0.5 ml PBS containing 1 mg (P2), 2 mg (P3), and 4 mg (P4) of Centella asiatica leaf extract. In ovo feeding of Centella asiatica leaf extract up to 4 mg significantly improved (p < 0.05) hatchability, villi height to crypt depth ratio, and leukocytes number, but had no significance (p > 0.05) on hatching weight, morphometric traits, physical score, weights of the proventriculus, gizzard, liver, thymus, colon, and relative length of the small intestine, cecum, and colon, as well as the number of hemoglobin, hematocrit, erythrocytes, leukocyte differentiation and the ratio of heterophils to lymphocytes. In ovo feeding of Centella asiatica leaf extract significantly reduced (p < 0.05) the weight of the heart, gallbladder, spleen, bursa of Fabricius, duodenum, jejunum, ileum, cecum, and crypt depth. It is concluded that in ovo feeding of Centella asiatica leaf extract at 4 mg improves the hatchability, immunity, and intestinal health without lowering the physical quality of Sentul chicks.

Indexed as

CentellaChickensIntestinesPlant ExtractsAnimal FeedAnimalsChick EmbryoIndonesiaPlant LeavesRandom AllocationTriterpenesCentella asiatica extractPlant ExtractsTriterpenesAntioxidantHatchabilityHerbsImmunityIn ovoSentul chick

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.