ArticlePsychopharmacology2025
Effects of nicotine-alcohol co-use on alcohol-induced blackouts and other alcohol-related consequences in college students.
Article in Psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- Contextual Moderators of the Relationship Between Alcohol-Induced Blackouts and Alcohol-Related Consequences Among Young Adults.Alcohol, clinical & experimental research · 2026Article
- Using Alcohol and Sleep Sensors to Understand Blackout Risk in Young Adults' Natural Settings (The Lights Out Study): Protocol for an Intensive Longitudinal Pilot Study.JMIR research protocols · 2026Article
- Mental health matters? An examination of how anxiety and depression influence the alcohol-e-cigarette use relationship.Addictive behaviors · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
rationaleAlcohol-induced blackouts (AIBs) are common in college students and are associated with other alcohol-related consequences. Alcohol-nicotine co-use is also common in this population. Nicotine has cognitive-enhancing properties impacting multiple cognitive domains, including those impaired by alcohol (e.g., attention), but it is unclear whether nicotine affects AIB risk or the relationship between AIBs and other alcohol-related consequences.
objectivesWe examined the moderating effects of nicotine use on the associations between (a) alcohol and AIBs and (b) AIBs and other consequences (total and serious: sexual, legal, or those with potential to cause great harm).
methodsCollege students who reported past semester heavy drinking and at least 1 AIB (N = 79, 55.7% female, 86.1% White) wore alcohol sensors and completed daily diaries over four consecutive weekends (89.9% completion). Multilevel models were conducted to test for moderating effects of nicotine (yes/no) on the alcohol-AIB relationship and the AIB-consequence relationship, adjusting for sex, race/ethnicity, and baseline nicotine use.
resultsConcurrent alcohol and nicotine use did not moderate the alcohol-AIB relationship, but weakened the associations between AIBs and both (1) total consequences and (2) serious consequences. On days with nicotine use, AIBs were associated with approximately 30% fewer total consequences and 50% fewer serious consequences than days without nicotine use.
conclusionsCollege students experienced fewer total and serious consequences on AIB nights when nicotine was used compared to AIB nights when nicotine was not used. Future research should explore potential mechanisms underlying the observed effects.
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