Evidence map›Paper›PMID 40493051›Full record

ReviewEuropean biophysics journal : EBJ2026

Microfluidics for protein interaction studies: current methods, challenges, and future perspectives.

Matthias M Schneider, Tuomas P J Knowles, Sandro Keller, Georg Krainer

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European biophysics journal : EBJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Biophysics Austria: 65 years history.European biophysics journal : EBJ · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthias M SchneiderCentre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Lensfield Road, Cambridge, CB2 1EW, UK.
Tuomas P J KnowlesCentre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Lensfield Road, Cambridge, CB2 1EW, UK. tpjk2@cam.ac.uk.
Sandro KellerBiophysics, Institute of Molecular Biosciences (IMB), NAWI Graz, University of Graz, Humboldtstr. 50/III, 8010, Graz, Austria. sandro.keller@uni-graz.at.
Georg KrainerCentre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Lensfield Road, Cambridge, CB2 1EW, UK. georg.krainer@uni-graz.at.ORCID http://orcid.org/0000-0002-9626-7636

Funding

ERC Starting Grant SignAlloMod 101164135UFO Award, Land Steiermark PN 3011
6 · The paper itself

Abstract

Proteins are the key molecular players of life, carrying out their functions through interactions. Microfluidic technologies have emerged as powerful tools for studying protein interactions with exquisite sensitivity, resolution, and throughput. In this review, we highlight recent advances in microfluidic approaches for protein interaction studies. We first explore continuous-flow microfluidics, which utilize diffusion-based techniques and electrophoretic methods, before examining the role of droplet microfluidics in probing protein interactions. We provide an overview of the diverse applications of these technologies in biophysical research, drug discovery, and clinical diagnostics. We conclude with a discussion of the potential of microfluidics for driving future innovations and emerging opportunities.

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsProtein Interaction MappingProteinsAnimalsHumansProteinsDiffusionDroplet microfluidicsFree-flow electrophoresisMicrofluidicsPhase separationProtein interactions

Identifiers

PMID40493051
PMCPMC13661635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.