Evidence map›Paper›PMID 40492764›Full record

ArticleMicrobiology spectrum2025

Evaluation of QuickMIC system for rapid antimicrobial susceptibility testing of Gram-negative pathogens from positive blood cultures, including strains producing extended-spectrum β-lactamases and carbapenemases.

Fabio Morecchiato, Chiara Chilleri, Alberto Antonelli, Christer Malmberg, Tommaso Giani, Gian Maria Rossolini

Abstract readEvaluation Study
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Evaluation of the NG-TESTJAC-antimicrobial resistance · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabio MorecchiatoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italy.
Chiara ChilleriDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italy.
Alberto AntonelliDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italy.ORCID 0000-0003-0295-6877
Christer MalmbergGradientech AB - Uppsala (Sweden), Uppsala, Uppsala County, Sweden.
Tommaso GianiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italy.ORCID 0000-0001-7293-058X
Gian Maria RossoliniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italy.ORCID 0000-0002-9386-0434

Funding

Italian Ministry of Health PAN-HUB 2021
6 · The paper itself

Abstract

The accuracy and turnaround time (TAT) of the QuickMIC system (QMIC) for rapid antimicrobial susceptibility testing (AST) of Gram-negative pathogens from positive blood cultures were evaluated, in comparison with a standard-of-care workflow based on culture and AST with broth microdilution. Essential agreement (EA) and bias were evaluated according to the ISO 20776-2:2021, category agreement (CA), categorical overestimation (CO), and underestimation (CU) rates were evaluated according to the European Committee on Antimicrobial Susceptibility Testing(EUCAST) breakpoints, and major discrepancy (MD) and very major discrepancy (VMD) rates were evaluated according to the Food and Drug Administration (FDA) guidelines and breakpoints. QMIC yielded evaluable data for 103/118 blood cultures (87.3%), including Enterobacterales (

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesGram-Negative BacteriaGram-Negative Bacterial InfectionsAcinetobacter baumanniiBacteremiaBlood CultureHumansMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemaseantimicrobial susceptibility testingblood culturesbloodstream infectionsdiagnosisrapid phenotypic antibiogram

Identifiers

PMID40492764
PMCPMC12210996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.