Evidence map›Paper›PMID 40492741›Full record

ArticlemBio2025

Stephanie B Orchanian, Sebastian Zolog, Julia Tomasello, Rijul Malik, Ji-Hun Shin, Anita A Koshy, Melissa B Lodoen

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. mBio · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie B OrchanianDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.ORCID 0000-0002-2491-1074
Sebastian ZologDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Julia TomaselloDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Rijul MalikDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Ji-Hun ShinDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.
Anita A KoshyNeuroscience Graduate Interdisciplinary Program, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0001-8705-3233
Melissa B LodoenDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.ORCID 0000-0002-3366-6840

Funding

Parasite dissemination in Toxoplasmic encephalitisR01AI120846 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LODOEN, MELISSA BRUCKNER · 2016 to 2020
$2.0M
Neuroimmunology Training Program at the University of California, IrvineT32NS121727 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kim Green, Thomas E Lane · 2022 to 2026
$854k
Neuroinflammation during cerebral Toxoplasma gondii infectionR21AI155122 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LODOEN, MELISSA BRUCKNER · 2021 to 2022
$395k
Regulation of Monocyte Entry to the Brain During NeuroinflammationF31NS118865 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ORCHANIAN, STEPHANIE · 2020 to 2023
$128k
National Institute of Allergy and Infectious Diseases R01AI120846National Institute of Allergy and Infectious Diseases R21AI155122NIAID NIH HHS R01 AI120846NIAID NIH HHS R21 AI155122NINDS NIH HHS F31 NS118865NINDS NIH HHS F31NS118865NINDS NIH HHS T32 NS121727NINDS NIH HHS T32NS121727
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

BrainMyeloid CellsToxoplasmaToxoplasmosis, AnimalToxoplasmosis, CerebralAnimalsChemokine CCL2Disease Models, AnimalFemaleMiceMice, Inbred C57BLMonocytesNF-kappa BReceptors, CCR2Chemokine CCL2NF-kappa BReceptors, CCR2brainimmune responsemonocytemyeloid cellsneuroinflammationToxoplasma gondii

Identifiers

PMID40492741
PMCPMC12239593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.