Evidence map›Paper›PMID 40492506›Full record

ArticleHIV medicine2025

Changes in characteristics and HIV-clinical outcomes of pregnant people living with HIV in the UK.

H Okhai, A Baskaran, L Bukasa, H Peters, C Thorne, C Sabin, UK Collaborative HIV Cohort

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In one paragraph

Article in HIV medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

H OkhaiInstitute for Global Health, University College London, London, UK.ORCID https://orcid.org/0000-0002-0549-4914
A BaskaranInstitute for Global Health, University College London, London, UK.
L BukasaGreat Ormond Street Institute of Child Health, University College London, London, UK.ORCID https://orcid.org/0000-0001-5775-1495
H PetersGreat Ormond Street Institute of Child Health, University College London, London, UK.
C ThorneGreat Ormond Street Institute of Child Health, University College London, London, UK.ORCID https://orcid.org/0000-0003-0389-1956
C SabinInstitute for Global Health, University College London, London, UK.ORCID https://orcid.org/0000-0001-5173-2760
UK Collaborative HIV Cohort

Funding

Medical Research CouncilNational Institute for Health and Care ResearchNIHR Great Ormond Street Hospital Biomedical Research Centre
6 · The paper itself

Abstract

objectiveIn this study, we explore changes in the demographic and clinical characteristics of pregnant people living with HIV, and their post-partum HIV outcomes between 2000 and 2018.

methodsWe described pregnancies resulting in a live birth from the linked UK CHIC/ISOSS dataset in three calendar periods (2000-2006; 2007-2012; 2013-2018). Thereafter, we explored median CD4 count change and viral rebound from delivery to 12 months post-partum.

resultsIn total, 4341 pregnancies were included. Maternal age increased from 31 (IQR: 28-35) years in 2000-2006 to 34 (IQR: 30-37) years in 2013-2018. Those conceiving in the most recent period had been diagnosed with HIV for longer (2000-2006: 3.0 years to 2013-2018: 7.5 years), had a higher median CD4 count (431-583 cells/mm

conclusionClinical management of pregnant people has changed over time, resulting in positive trends in this study both within pregnancy and post-partum. Further work needs to understand what barriers remain for those who do not achieve optimal management of HIV in the post-partum period.

Indexed as

HIVoutcomespostpartumpregnancy

Identifiers

PMID40492506
PMCPMC12315076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.