Evidence map›Paper›PMID 40492501›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Ultrasound-Induced Nitric Oxide-Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime.

Xue Xu, Jinxu Cao, Yan Mu, Hao Zhang, Ya-Lei Wang, Mengzhen Chen, Yuce Li, Qian Hua

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xue XuSchool of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.ORCID https://orcid.org/0000-0001-6045-3712
Jinxu CaoSchool of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Yan MuSchool of Life Sciences, School of Chinese Medicine, Beijing University of Chinese medicine, Beijing, 100029, China.
Hao ZhangSchool of Life Sciences, School of Chinese Medicine, Beijing University of Chinese medicine, Beijing, 100029, China.
Ya-Lei WangSchool of Life Sciences, School of Chinese Medicine, Beijing University of Chinese medicine, Beijing, 100029, China.
Mengzhen ChenSchool of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Yuce LiCollege of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, 430065, China.ORCID https://orcid.org/0000-0003-0656-3149
Qian HuaSchool of Life Sciences, School of Chinese Medicine, Beijing University of Chinese medicine, Beijing, 100029, China.

Funding

Beijing Nova Program 20220484162Department of Education of Hubei Province, China Q20231110National Natural Science Foundation of China 82274370Wuhan Science and Technology Bureau, China 2023020201020405
6 · The paper itself

Abstract

Cancer treatment is often ineffective due to poor bioimaging and resistance to standard therapies. This issue is exacerbated by multiple low-penetrable bio-barriers that limit the theranostic agents' effectiveness in tumors. Here, a hollow nanomotor PM-HMSN/Arg is fabricated by a sequential process involving: electrostatic adsorption of Mn

Indexed as

NeoplasmsNitric OxideTheranostic NanomedicineAnimalsCell Line, TumorHumansMiceNitric Oxidenanomotornitric oxide therapytumor penetrationultrasonic bioimaging

Identifiers

PMID40492501
PMCPMC12376693

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.