Evidence map›Paper›PMID 40492436›Full record

ArticleJournal of diabetes investigation2025

METTL3/YTHDF3 m

Jinmei Zhang, Xiaoping Zhou, Bin Wang, Yan Yin, Daihao Wei, Kun Li

Abstract read
In one paragraph

Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. TRMT6-directed mNPJ precision oncology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jinmei ZhangDepartment of Endocrine, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Xiaoping ZhouDepartment of Endocrine, Changyi Traditional Chinese Medicine Hospital, Weifang, Shandong, China.
Bin WangDepartment of Endocrine, Weifang High Tech Rehabilitation Hospital, Weifang, Shandong, China.
Yan YinDepartment of Endocrine, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Daihao WeiDepartment of Endocrine, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Kun LiDepartment of Nephrology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China.ORCID https://orcid.org/0009-0006-0872-6713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDiabetic kidney disease (DKD) is a common complication of diabetes. N6-Methyladenosine (m

methodsThirty-five DKD patients and 28 control volunteers were recruited. Animal and cell DKD models were established. QRT-PCR and Western blot were performed to analyze the expression of METTL3 and fibrosis-related indicators. Cell viability and proliferation were assessed via a cell counting kit-8 and colony formation assays. Ferrous iron (Fe

resultsResults showed that METTL3-mediated m

conclusionsIn summary, METTL3/YTHDF3 m

Indexed as

AdenosineAntigens, CDDiabetic NephropathiesFerroptosisMethyltransferasesReceptors, TransferrinRNA-Binding ProteinsAnimalsCase-Control StudiesCell ProliferationFemaleHumansMaleMesangial CellsMiceMice, Inbred C57BLAdenosineAntigens, CDCD71 antigenMethyltransferasesMETTL3 protein, humanN-methyladenosineReceptors, TransferrinRNA-Binding ProteinsDiabetic kidney diseaseFerroptosisMETTL3

Identifiers

PMID40492436
PMCPMC12400356

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.