Evidence map›Paper›PMID 40492256›Full record

ArticleJAC-antimicrobial resistance2025

Genomic diversity of clinically relevant bacterial pathogens from an acute care hospital in Suva, Fiji.

Jane Hawkey, Michael J Loftus, Amitesh Prasad, Timoci Vakatawa, Vinita Prasad, Litia Tudravu, Katherine Pragastis, Jessica Wisniewski, Taylor Harshegyi-Hand, Luke Blakeway and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAC-antimicrobial resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jane HawkeyDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.ORCID https://orcid.org/0000-0001-9661-5293
Michael J LoftusDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.ORCID https://orcid.org/0000-0001-6672-0578
Amitesh PrasadPathology Department, Colonial War Memorial Hospital, Suva, Fiji.
Timoci VakatawaPathology Department, Colonial War Memorial Hospital, Suva, Fiji.
Vinita PrasadPathology Department, Colonial War Memorial Hospital, Suva, Fiji.
Litia TudravuPathology Department, Colonial War Memorial Hospital, Suva, Fiji.
Katherine PragastisDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Jessica WisniewskiDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Taylor Harshegyi-HandDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Luke BlakewayDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Andrew J StewardsonDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Adam W JenneyDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.
Anton Y PelegDepartment of Infectious Diseases, the Alfred Hospital and School of Translational Medicine, Monash University, Melbourne 3004, Australia.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objectives: Antimicrobial resistance (AMR) is a global health threat, with third-generation cephalosporin-resistant (3GCR) and carbapenem-resistant infections of particular concern. There is currently a lack of genomic data on AMR organisms in the Pacific region. Methods: We aimed to address this gap by examining the genetic diversity of a collection of 788 Gram-negative and Gram-positive clinical isolates collected between July 2020 and October 2022 from a single hospital in Suva, Fiji. We sampled sensitive and resistant isolates, focusing on 3GCR and carbapenem-resistant Gram-negatives, and methicillin-resistant Results: We detected 29 distinct species across 12 different genera. Amongst Gram-negative genomes, Conclusions: This study provides crucial genomic data on AMR organisms in Fiji, highlighting the diversity of resistant species in the region. Local transmission of four carbapenem-resistant clones within Fiji was observed, underscoring the importance of local spread of these resistant strains.

Identifiers

PMID40492256
PMCPMC12147017

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.