ReviewEcancermedicalscience2025
Current advances in cancer immunohistochemistry: a new perspective for the Ki-67 biomarker.
Review in Ecancermedicalscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- A transformer-based multimodal deep learning model for preoperative prediction of Ki-67 expression level in glioma.BMC medical imaging · 2026Article
- Roburic Acid as a Therapeutic Candidate: Antiproliferative Activity and Secondary Cell Death Response in Colorectal Cancer Cells.International journal of molecular sciences · 2026Article
- Histopathological and ultrastructure alterations in tongue and parotid tissues of rats in consequence to long-term alcohol intoxication and ameliorative role of 10-dehydrogingerdione.BMC oral health · 2026Article
- From Classical to Emerging Biomarkers of Brain and Central Nervous System Tumors. An Evidence-Based Review with a Focus on Gliomas.Cellular and molecular neurobiology · 2026Review
- UCP2 Identifies Immunosuppressive Tumor-Associated Macrophages and Is Associated with Predicted Immunotherapy Resistance in Glioma.Oncology research · 2026Article
- Small-cell neuroendocrine carcinoma of the descending colon in a young adult: a case report.Frontiers in oncology · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ki-67 is a cell proliferation biomarker used to evaluate the proliferative activity of neoplasia cells. However, considering its functions on the cell cycle, the standard method seems to be an underused way of evaluating expression, since so far, its analytical validity of Ki-67 remains questionable for its use in personalised therapy. Improvements in the assessment of Ki-67 expression continue to be explored, and recently, a new approach that considers the heterogeneity or variability in staining intensity has emerged as a more improved way than the traditional method. In this review, we bring together what is available in the literature on the biological properties of the protein and highlight how this potential association is promising in the field of personalised medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.