Evidence map›Paper›PMID 40492084›Full record

ArticlemedRxiv : the preprint server for health sciences2025

The rise and global spread of IMP carbapenemases (1996-2023): a genomic epidemiology study.

Ben Vezina, Bhargava Reddy Morampalli, Hoai-An Nguyen, Angela Gomez-Simmonds, Anton Y Peleg, Nenad Macesic

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ben VezinaDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID 0000-0003-4224-2537
Bhargava Reddy MorampalliDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID 0000-0003-2741-6826
Hoai-An NguyenDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID 0000-0001-5345-2957
Angela Gomez-SimmondsDivision of Infectious Diseases, Department of Internal Medicine, UC Davis Health, Sacramento, California, USA.ORCID 0000-0001-5078-7137
Anton Y PelegDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID 0000-0002-2296-2126
Nenad MacesicDepartment of Infectious Diseases, The Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Australia.ORCID 0000-0002-7905-628X

Funding

Genetic Factors associated with phenotypic beta-lactam resistance in extended-spectrum beta lactamase-producing EnterobacteralesR01AI175414 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Angela Gomez-Simmonds · 2024 to 2026
$1.4M
NIAID NIH HHS R01 AI175414
6 · The paper itself

Abstract

Background: IMP carbapenemases confer extensive drug resistance and are increasingly noted worldwide. Despite this, little is known regarding the global epidemiology of IMP carbapenemases. Methods: We comprehensively identified Findings: 4,556 Interpretation: Global analysis enabled us to historically reconstruct the emergence and variant-specific epidemiologies of Funding: NHMRC EL1 (APP1176324) to N.M.; NHMRC PF (APP1117940) to A.Y.P.; NIH/NIAID R01AI175414 to A.G-S.

Identifiers

PMID40492084
PMCPMC12148276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.