Evidence map›Paper›PMID 40492068›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Shifting Dynamics of DENV2 in Costa Rica: Emergence of the Cosmopolitan Genotype (2024).

Mauricio Gonzalez Elizondo, Dihala Picado Soto, Estela Cordero Laurent, Francisco Duarte Martínez, Luiz Carlos Junior Alcantara, Vagner Fonseca, Jairo Andrés Méndez Rico, Jose Lourenco, Leticia Franco, Marta Giovanetti and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Mauricio Gonzalez ElizondoInstituto Costarricense de Investigación y Enseñanza en Salud y Nutrición - Centro Nacional de Referencia de Virología. Tres Ríos, La Unión, Cartago, Costa Rica, Centroamérica. 30301.
Dihala Picado SotoInstituto Costarricense de Investigación y Enseñanza en Salud y Nutrición - Centro Nacional de Referencia de Virología. Tres Ríos, La Unión, Cartago, Costa Rica, Centroamérica. 30301.
Estela Cordero LaurentInstituto Costarricense de Investigación y Enseñanza en Salud y Nutrición - Centro Nacional de Referencia de Virología. Tres Ríos, La Unión, Cartago, Costa Rica, Centroamérica. 30301.
Francisco Duarte MartínezInstituto Costarricense de Investigación y Enseñanza en Salud y Nutrición - Centro Nacional de Referencia de Virología. Tres Ríos, La Unión, Cartago, Costa Rica, Centroamérica. 30301.
Luiz Carlos Junior AlcantaraRené Rachou Institute, Oswaldo Cruz Foundation, Belo Horizonte, Brazil University; Stellenbosch, South Africa.
Vagner FonsecaDepartment of Exact and Earth Sciences, University of the State of Bahia, Salvador, Brazil.ORCID 0000-0001-5521-6448
Jairo Andrés Méndez RicoPan American Health Organization/World Health Organization, Washington, DC, USA.
Jose LourencoUniversidade Católica Portuguesa, Católica Medical School, Católica Biomedical Research Centre, Portugal.
Leticia FrancoPan American Health Organization/World Health Organization, Washington, DC, USA.
Marta GiovanettiDepartment of Sciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, Italy.
Claudio Soto GaritaInstituto Costarricense de Investigación y Enseñanza en Salud y Nutrición - Centro Nacional de Referencia de Virología. Tres Ríos, La Unión, Cartago, Costa Rica, Centroamérica. 30301.

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
NIAID NIH HHS U01 AI151698
6 · The paper itself

Abstract

Dengue remains a major public health challenge. In Costa Rica, we implemented the first nationwide genomic surveillance to track the emergence of the DENV2 Cosmopolitan genotype. Phylogenetic and eco-epidemiological analyses revealed early detection, climate-linked spread, and spatial heterogeneity. Findings underscore the need for integrated surveillance to guide adaptive responses to emerging arboviral threats.

Indexed as

Cosmopolitan genotypeCosta RicaDengue viruseco-epidemiological modellinggenomic monitoring

Identifiers

PMID40492068
PMCPMC12148270

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.